Sourced from ClinicalTrials.gov · NIH/NLM registry

1,279 APOE4 trials.
Refreshed every 24h.

Every clinical trial relevant to APOE4 carriers — translated into plain English, curated by Phoenix, refreshed daily.

Last refresh: 23h ago
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Phoenix members answer 6 questions about APOE genotype, cognitive status, and medical history → see only trials they're likely eligible for. Members typically rule out 84% of the list in 60 seconds.

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Showing 500 of 500 loaded trials

NCT06797817Phase 3Not yet recruiting

Tributyrin Treatment in Mild Alzheimer Disease: Assessment of Butyrate Effects Via the Gut-Brain

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06956300N/ARecruiting

TMS for Cognitive Decline in Aging and Preclinical AD

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06719297N/ANot yet recruiting

Cognitive Integrated Motor Training (CM) to Improve Gait and Balance and Reduce Falls in Older Adults With Mild Cognitive Impairment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07037550N/AActive

Effectiveness of Strength-based Intervention for Elderly With Dementia Living in the Community

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06705478Phase 2Recruiting

Pramipexole Versus Escitalopram to Treat Major Depressive Disorder (MDD) and Comorbid MDD With Mild Neurocognitive Disorder (MND) in Persons With HIV

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
40 sites
NCT06875986Recruiting

REXULTI Drug General Use-results Survey (Excessive Motor Activity or Physically/Verbally Aggressive Behavior Due to Rapid Changes in Mood, Irritability, and/or Outbursts Associated With Dementia Due to Alzheimer's Disease)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

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NCT05144516N/ARecruiting

Cancer and Mild Cognitive Impairment Dyadic Intervention

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05196984N/ARecruiting

Gamma Frequency Stimulation in Individuals With Down Syndrome

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06104852Recruiting

Triage Survey for Neurology Research Eligibility

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
3 sites
NCT06194006N/ANot yet recruiting

Long Term Follow-up Grafted Huntington's Disease Patients

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06375213Recruiting

Investigating Neurocognitive Disorders Epidemiology

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05785910N/AActive

Adaptation of the Uniform Data Set for Telematic Administration

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

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NCT05746715Recruiting

A Natural History Study of Preclinical Genetic Creutzfeldt-Jakob Disease (CJD)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05460143Recruiting

Optical Neuroimaging and Cognition

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06974890N/ARecruiting

Effects of Shuttle Balance Training on Balance , Gait and Postural Control in Children With Mild Cognitive Impairment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07422038Not yet recruiting

BioMIND (Biomarkers for the Molecular Identification of Neurodegenerative Dementia) - Improving Access to Alzheimer's Disease Diagnostics: A Pragmatic System Level Intervention

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
NCT07346794N/ANot yet recruiting

The Underlying Neural Mechanism of TMS in Improving the Imbalance of "Microbiota-brain-gut Axis" in Alzheimer 's Disease Population

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
NCT06628427Not yet recruiting

Unlock the Secrets of Ageing Brains Through P300 Brain-computer Interface Games

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

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NCT05109169Phase 2Recruiting

METformin and FINGER Intervention to Prevent Cognitive Impairment and Disability in Older Adults at Risk for Dementia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
3 sites
NCT07550075N/ANot yet recruiting

Caring for Dementia Caregivers in Ethnic Immigrant Communities

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05826457Recruiting

North American Prodromal Synucleinopathy Consortium Stage 2

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
9 sites
NCT05532657Phase 3Active

ACHIEVE Brain Health Follow-Up Study

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
4 sites
NCT07204145N/ANot yet recruiting

Laser Acupuncture for Behavioral and Psychological Symptoms of Dementia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
2 sites
NCT07512362Phase 2Not yet recruiting

Human Mesenchymal Stem Cells & Monoclonal Antibodies in the Treatment for Mild Cognitive Impairment or Early Alzheimer's Disease.

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

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NCT03860857Phase 3Recruiting

Biomarker Exploration in Aging, Cognition and Neurodegeneration

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05260177N/ARecruiting

Study on the Effect of 40 Hz Non-Invasive Light Therapy System

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05386394Phase 2Recruiting

Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
3 sites
NCT05373745N/AActive

Managing Pain and Cognitions in Older Adults With Early Cognitive Decline and Chronic Pain

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06938100Recruiting

Genotype, Clinical Features and Imaging of Neuroradiological Abnormalities in CADASIL

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
2 sites
NCT03672201N/AActive

Standardizing Care for Neuropsychiatric Symptoms and Quality of Life in Dementia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
6 sites
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

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NCT05944601N/AActiveAPOE4-explicit

Exploring to Remediate Behavioral Disturbances of Spatial Cognition

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06782230Recruiting

ScATtEred Rare Disease Biobanks: a Model of Sample/Data Collection With susTainablE and Shared Criteria

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT04575337RecruitingAPOE4-explicit

Study on Biomarkers for Early Diagnosis of Alzheimer's Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07092371N/ANot yet recruiting

Smartphone Multimodal Health Intervention for Neurological Enhancement (SHINE)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06416137Not yet recruiting

Dementia in Migrants Living in Italy: Promoting a Diversity-sensitive Clinical Approach and Provision of Care

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
NCT06867692N/ARecruiting

Effects of Aerobic Exercises on Dual-task Performance and Motor Skills in Children With Mild Cognitive Impairment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT06933212Recruiting

Effect of the Mediterranean Diet in Patients Affected by CADASIL and Cerebral Amyloid Angiopathy.

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05528302N/AActive

Technology Assisted Cognitive Behavioural Therapy Intervention for Anxiety in People Living With Cognitive Impairment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
5 sites
NCT07010705Recruiting

Digital Measures for Clinical Trial Endpoints in Huntington's Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05697588Recruiting

Exploring the Predicting Biomarkers From Mild Cognitive Impairment to Dementia (EBMID)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06817876N/ARecruiting

Connecting Caregivers With Community Services: The Care Buddy Platform

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06523296N/ARecruiting

Presence of Anti-RACH Antibodies and Neurocognitive Disorder in Myasthenic or Alzheimers's Patients.

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT07264283Phase 2Not yet recruiting

The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen B: LM11A-31

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
NCT03840083N/ARecruiting

Sleep-dependent Learning in Aging

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06079203N/AActive

ED-LEAD: Emergency Departments Leading the Transformation of Alzheimer's and Dementia Care

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07342569N/ANot yet recruiting

The WeACT Program for Family Caregivers of People Living With Dementia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06448403Recruiting

Multimodal Assesment of Alzheimer Patients

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06687161N/ARecruiting

Treating Insomnia in Mild Cognitive Impairment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT07414680Not yet recruiting

Integrating Systematic Data of Medicine to Explore the Solution for Healthy Aging (ISDHA) Phase 4

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
2 sites
NCT06279325N/ARecruiting

Effects of a Computerized Cognitive Stimulation Intervention Adapted to the Level of Cognitive Reserve

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07213284N/ANot yet recruiting

Michigan Healthy Mom (MI-MOM) Pregnancy Improvement Web Application Trial

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
NCT06286293Not yet recruiting

YOD-RiSoCo: Social Cognition and Risk-taking Behaviour in Patients with Young-onset Dementia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
NCT07230158N/ANot yet recruiting

Transcranial Alternating Current Stimulation for Patients With Mild Alzheimer's Disease II (TRANSFORM-AD II)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06978946N/ANot yet recruiting

Deep Cervical Lymphaticovenous Anastomosis Surgery for Moderate-to-Advanced Dementia Patients

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT04863859Recruiting

Persons With Dementia and Their Extended Family Caregivers

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06005038Phase 1Recruiting

CogT pSOPT Intervention Study

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05919485N/ARecruiting

The Effects of Specific tDCS on Cognition in MCI

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06092125Recruiting

Clinical Applicantion of Multi-Tracer PET/MR Imaging in Neurological Disorders/Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05927974Recruiting

Investigating Dynamic Interactions in Distributed Cognitive Control Networks

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06298474N/ARecruiting

The BRAIN App (Phase 2 SBIR)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT06352710Recruiting

Determining Postoperative Recovery and the Impact of Adverse Events in Neurosurgery Based on Self-reported, App-based Longitudinal Assessment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07089654N/ANot yet recruiting

Evaluation of a PMT Rehabilitation Nursing Plan for the Older Adults With MCI to Promote Cognitive Health

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
2 sites
NCT07318038N/ARecruiting

The Use of Rhythmic Light Therapy in Mild Cognitive Impairment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07006155N/ARecruiting

Biograph Vision 600 Versus Biograph Vision.X PET/CT

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06322667Recruiting

A Post Marketing Study in Participants With Early Alzheimer's Disease Treated With Lecanemab

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
3 sites
NCT04599764N/ARecruiting

High Definition Transcranial Direct Current Stimulation (HD-tDCS) for Early Alzheimer's Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT06607900Phase 1Not yet recruiting

hUC-MSC-sEV-001 Nasal Drops for Neurodegenerative Diseases

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT04801589Phase 3Recruiting

Goal-Directed Sedation in Mechanically Ventilated Infants and Children

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT03493178Early Phase 1Active

Glutathione in Mild Cognitive Impairment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06150352Recruiting

Sleep Apnea, Neurocognitive Decline and Brain Imaging in Patients With Subjective or Mild Cognitive Impairment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07479914N/AActive

Art of Memory for Cognitive Enhancement in the Monza Brain Health Service

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07454824N/ARecruiting

e-ALIGN: A Patient Portal-based Intervention to Align Medications With What Matters Most

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT06534658Recruiting

Study on Multimodal Imaging and Molecular Imaging Techniques in Degenerative Dementia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
8 sites
NCT06621758Not yet recruiting

Communication Regarding Preclinical Dementia Diagnostic and Diagnostic Disclosure Among Patients with MCI and SCD

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
NCT04956549N/ARecruiting

Reducing African American's Alzheimer's Risk Through Exercise-Mild Cognitive Impairment (RAATE-MCI)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06808984Phase 2Recruiting

Study to Evaluate the Efficacy, Safety, and Tolerability of BMS-986368, for the Treatment of Agitation in Participants With Alzheimer's Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
52 sites
NCT06852352N/ARecruiting

An Exploratory Study to Confirm Efficacy of Modified Deep Cervical Lymphovenous Anastomosis (LVA) in Alzheimer's Disease/ Parkinson's Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07212062Phase 2Not yet recruiting

The Purpose of This Study is to Evaluate the Safety and Tolerability of X/T+X-EC in Participants With Alzheimer's Disease Who Are Currently Treated With Lecanemab.

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT05187819N/ARecruiting

Blood-based Biomarkers for Diagnosis of Alzheimer's

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT03403257Active

Brain Attack Surveillance in Corpus Christi--Cognitive (BASIC-Cognitive)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06756828N/ANot yet recruiting

Effects of 3-Month Melatonin Treatment on Regional Cerebellar Structure and Blood Biomarkers in Alzheimer's Disease Spectrum

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
NCT06826612Phase 1Recruiting

A Randomized Study of SPK-10001 Gene Therapy in Participants With Huntington's Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
5 sites
NCT06949865Recruiting

AI-Enhanced Optimization of Acute Levodopa Challenge Test

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06618807N/ARecruiting

Infrared Light for Memory Loss in Mild Cognitive Impairment (MCI)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT06883019Recruiting

Lecanemab for Early Onset Familial Alzheimer's Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
15 sites
NCT06217575N/ARecruiting

Brain Research Assessing Impacts of Neurophysiological Processing Speed Training in Veterans

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05552157Phase 2Recruiting

A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset AD Caused by a Genetic Mutation

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
35 sites
NCT06877182Active

Novel Neuroradiological Workflow for the Assisted DIAgnosis and Management of DEMentia with Artificial Intelligence

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07305415N/ARecruiting

Integrative Therapeutic Programme to Regulate Expressed Emotions Among Informal Caregivers of People With Dementia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT04430517Early Phase 1ActiveAPOE4-explicit

Effects of Nicotinamide Riboside on Bioenergetics and Oxidative Stress in Mild Cognitive Impairment/Alzheimer's Dementia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT07154485Phase 2Not yet recruiting

Investigator Initiated Study for the Safety and Efficacy in Frontotemporal Dementia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
NCT06263920Recruiting

Neurofrailty: A Study of Late-onset Epilepsy and Its Associations

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06791720N/ANot yet recruiting

Effects of Music-with-Movement on Cognitive and Physical Performance of People With Potentially Reversible Cognitive Frailty: a Randomised Controlled Trial

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06862960Phase 2Not yet recruiting

Ozanimod in Patients With Alzheimer's Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
NCT06181513Early Phase 1Recruiting

Probiotics in Mild Alzheimer's Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07386808N/AActive

Improvement of Sleep Disorders in Patients With Alzheimer's Disease After Sunlight Exposure Therapy.

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT03116126Phase 3Active

Noradrenergic Add-on Therapy With Guanfacine

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT04141878N/ARecruiting

Dementia and Diabetes Prevention Program

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05928247N/ARecruiting

Manualized Assessment and Treatment Model of Challenging Behavior

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06604507Not yet recruiting

Feasibility of Using an App for Managing Phantom Limb Pain Associated with Combat Injury in Ukraine (PAMELA)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
5 sites
NCT06340659N/ARecruiting

Concurrent Aerobic Exercise and Cognitive Training to Prevent Alzheimer's in At-risk Older Adults (The Exergames Telerehabilitation Study)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06539403Recruiting

Thinking About Memory: How Confident Are You in Your Memory, and Does it Change With Age?

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT06768996N/AActive

Music, Social Attention, and Dementia

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05375513N/ARecruiting

SYNERGIC-2 Trial (SYNchronizing, Exercises and Remedies to GaIn Cognition@home)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
8 sites
NCT03454646Phase 4Not yet recruiting

Comparison of Therapeutic Strategies With Cholinesterase Inhibitors (SOS TRIAL)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
31 sites
NCT06705010N/ANot yet recruiting

Monitoring of Brain Metabolites Using Proton and Deuterium MR Techniques

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06466460N/ARecruiting

Motion-based Interactive Technology for Improved Quality of Life in Individuals With Cognitive Impairment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05614310Recruiting

Detecting Early Alzheimer's Using MR

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT05625425N/ARecruiting

Wayfinding Intervention and Long-Term Memory

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06362824N/ARecruiting

Promoting Physical Activity in Older Hispanic/Latino(a) Adults

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
2 sites
NCT06690983Recruiting

Tau PET/CT in Various Tau-Related Disease Patients

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
2 sites
NCT05968703N/ARecruiting

Combined STN and NBM Deep Brain Stimulation for Mild Cognitive Impairment in Parkinson's Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05924425Phase 4Recruiting

Daridorexant to Treat Insomnia in Patients With Mild Cognitive Impairment and Mild to Moderate Alzheimer Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT05495087N/ARecruiting

IHT for Mild Cognitive Impairment

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT07312435N/ARecruiting

B-vitamins and Omega-3 Fatty Acids and Biomarkers of Brain Atrophy.

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT04408625Phase 1Active

Phase 1/2 Clinical Trial of LY3884963 in Patients With Frontotemporal Dementia With Progranulin Mutations (FTD-GRN)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
12 sites
NCT07369258N/ARecruiting

Clinical Application of Listening to Music to Prevent Delirium in the Intensive Care Unit

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06174038N/ARecruiting

Early Age-Related Hearing Loss Investigation (EARHLI)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT06991816Active

The Brain&Senses Study

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT03754725Phase 1Recruiting

Ferritin and Iron Burden in SAH sIRB

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
2 sites
Phoenix membership

Eligibility is the bottleneck.

80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

Join Phoenix
NCT06452147N/ARecruiting

Anesthesia and Perioperative Neurocognitive Disorders in the Elderly Patients Undergoing Hip Fracture Surgery Platform Trial (ANDES Platform Trial)

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
NCT07435467Recruiting

Blood Biomarkers for Alzheimer Disease and Neuro-injury to Estimate the Association With Cognitive/Functional Decline and Mortality in a Real-world Population of GERiatric Hospitalized Patients (BAD-GER)

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3 sites
NCT07204977Phase 1Active

Acamprosate in C9orf72 Hexanucleotide Repeat Expansion Amyotrophic Lateral Sclerosis (ACALS)

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1 site
NCT07521865Active

Remote Technologies in Early Stages of Alzheimer's Disease

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1 site
NCT06972030N/ANot yet recruiting

Motivational Interviewing-Based Training

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1 site
NCT06840054Phase 2Not yet recruiting

The Safety and Efficacy of Sodium Pentaborate Pentahydrate in Patients With Mild to Moderate Alzheimer's Disease

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NCT07377981Phase 4Not yet recruiting

An Exploratory Study of the Efficacy and Safety of Esketamine and Dexmedetomidine in Non-Intubated ICU Patients With Hyperactive Delirium: Protocol of a Randomized Controlled Trial

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1 site
NCT05985486N/ARecruiting

Brain Outcomes With Lifestyle Change in Down Syndrome

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1 site
NCT06496945Recruiting

Assessing the Impact of DAy Programs on Individuals Living with Dementia and Their Family/friend Caregivers

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4 sites
NCT06976294N/ANot yet recruiting

The Effects of Cognitive Behavioral Approach-Based Psychoeducation on Caregivers of Alzheimer's Patients

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NCT05655195N/ARecruiting

Chronic Treatment of Alzheimer's Disease by Gamma Light and Sound Therapy

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1 site
NCT06565169N/ARecruiting

Improving PCP Advance Care Planning for People With ADRD

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1 site
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NCT06955494N/ARecruiting

ENACT Program on Auditory Perception and Function, Cognitive Function and Health-related Quality of Life

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1 site
NCT07130669Phase 1Recruiting

FACE Phase II (a Stage II Trial)

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1 site
NCT04289402N/AActive

Individualized Brain Stimulation to Improve Mobility in Alzheimer's Disease

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1 site
NCT05653141Active

Post-stroke Cognitive Impairment

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1 site
NCT06691256Phase 2Active

Preventing Medication Mismanagement in People Living with Dementia Through Automated Medication Dispensing with Facial Recognition and Video Observation

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1 site
NCT06781749Recruiting

New Approach to Objectively Measure Social Engagement in Older Adults With Hearing Loss

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2 sites
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NCT06079216N/ANot yet recruiting

Making Connections Thru Music

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1 site
NCT02951598Active

A Study of Health Care Use and Costs in Participants With Early Stage Alzheimer's Disease (AD)

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77 sites
NCT06492109N/ARecruiting

The Peripheral Blood Multi-Omics Study on Sleep Loss

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1 site
NCT03848312Phase 3Recruiting

Preventing Alzheimer's With Cognitive Training

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7 sites
NCT05799001N/ARecruiting

Dance Workshop for Institutionalized Seniors With Behavioral and Psychological Symptoms of Dementia

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2 sites
NCT06836141Recruiting

Biomarkers for Cognitive Decline in Intracerebral Hemorrhage

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1 site
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NCT04042922N/AActive

High Frequency Light and Sound Stimulation to Improve Brain Functions in Alzheimer's Disease

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1 site
NCT05791994N/ARecruiting

EVASION: Effect of VisuAl Stimulation on attentION

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1 site
NCT06619327N/ARecruiting

Resilient Together for Dementia (RT-D)

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1 site
NCT06264258N/ARecruiting

Game-based Pediatric Diabetes Education

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1 site
NCT06860035N/ARecruiting

Dementia Caregivers' Link to Assistance and Resources

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1 site
NCT06662526Phase 4Not yet recruiting

Lithium for Prevention of Cognitive Declining in Mood Illnesses

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2 sites
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NCT07064226N/ARecruiting

Validation of a Digital Intervention to Rehabilitate Cognitive Resources

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1 site
NCT06704971Active

Assessing Cognitive Decline at Home

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1 site
NCT06585787Phase 3Recruiting

A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)

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288 sites
NCT07341009Recruiting

Evaluation of a Neuropsychological Tool to Assess Temporal Processing Abilities in Alzheimer's Disease

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1 site
NCT05558709N/ARecruiting

Social-cognitive Functioning: Validation of a New Neuropsychological Test

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1 site
NCT07516899Phase 1Not yet recruiting

Mass Balance Study of [14C] LPM3770164 in Healthy Participants

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1 site
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NCT07485387Recruiting

Global Collaborative Research on Establishing a Korean Cognitive Aging Cohort

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1 site
NCT07431164N/AActive

Augmented Reality-Based Aromatherapy Education for Older Adults With Early-Stage Dementia in Taiwan

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1 site
NCT07041034N/ANot yet recruiting

SUNAM Protocol for Managing BPSD

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NCT03665831N/ARecruiting

Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults

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1 site
NCT04437511Phase 3Active

A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2)

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274 sites
NCT07356336N/ARecruiting

Cognitive Model for Behavioral Interventions as a Non-pharmacological Intervention for Behavioral and Psychological Symptoms of Dementia

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1 site
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NCT04274998Early Phase 1Active

Neuroinflammation Imaging in AD

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1 site
NCT06506487N/AActive

Effectiveness of Doll Therapy in People With Dementia

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1 site
NCT06064890Phase 1Recruiting

A Study to Evaluate the Safety and Effect of AVB-101, a Gene Therapy Product, in Subjects With a Genetic Sub-type of Frontotemporal Dementia (FTD-GRN)

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19 sites
NCT03452878Active

Evaluation of the Functional Results of Bilateral Amygdalotomy for Refractory Aggressive Patients

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NCT06130735N/ARecruiting

Impact of Intensive Computerized Cognitive Training

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1 site
NCT06160908N/AActive

Transcranial Near-infrared Light Therapy for Mild-Moderate Alzheimer's Disease (NIR4AD)

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1 site
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NCT07018726N/ARecruiting

Addressing Emotional Distress in Dyads of Persons With a Young Onset Dementia (YOD) and Their Care-partners

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1 site
NCT07073443N/AActive

Evaluation of the Effect of Memory-based Reminiscence Therapy

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1 site
NCT05858996Phase 2Recruiting

Testing the Pain Clinical Practice Guideline

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7 sites
NCT05077579Recruiting

Alzheimer"s Imaging Biomarkers in Obesity

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1 site
NCT04240561N/ARecruiting

Characterizing Variability in Hearing Aid Outcomes in Among Older Adults With Alzheimer's Dementia

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2 sites
NCT06803823Phase 2Recruiting

A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease Dementia

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38 sites
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NCT07467460Recruiting

Precision Medicine and Neurodegenerative Diseases: Advanced Systems for the Diagnosis and Treatment of Parkinson's Disease and Alzheimer's Disease.

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1 site
NCT07397182N/ANot yet recruiting

SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment

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1 site
NCT04748861N/AActiveAPOE4-explicit

CYCLE-AD (CYcling to Cease or Limit the Effects of Alzheimer's Disease)

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1 site
NCT06965062N/ARecruiting

Cervical Lymphatico-Venous Bypass for Treatment of Alzheimer's Disease - Proof of Concept Study (CLyVeB-AD-1 Study)

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1 site
NCT05623124Recruiting

Ruijin Neurobank of Alzheimer's Disease and Dementia

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1 site
NCT07206446N/ANot yet recruiting

A Prospective Evaluation of a Prescription Digital Therapeutic for Treatment of Overactive Bladder in Women: The RiSolve Trial

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Phoenix membership

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NCT07370311N/ARecruiting

A Culturally Adapted Decision Aid Intervention to Support Chinese American Dementia Caregivers in Feeding-Related Decisions

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1 site
NCT04852601N/AActive

ToolBox Detect: Low Cost Detection of Cognitive Decline in Primary Care Settings

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1 site
NCT04855630N/ARecruiting

Combating Alzheimer's Through Sleep and Exercise

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1 site
NCT06451692N/ARecruiting

Prioritising Patient Medication Review: Hospitals Reaching Out

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1 site
NCT07546409N/AActive

Effects of Exogenous Ketones on Cognitive Function in Older Adults With Prediabetes?

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2 sites
NCT04850053Recruiting

Detection of Alzheimer's Disease (AD)-Related Seeds for AD Diagnosis

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1 site
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NCT06711952N/ARecruiting

German Validation Study of the Subjective Cognitive Decline Questionnaire (SCD-Q)

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1 site
NCT03047369Recruiting

The Myelin Disorders Biorepository Project

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23 sites
NCT03113461N/AActive

MCI: CPAP Treatment of OSA (Memories2)

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4 sites
NCT05801380Recruiting

Monitoring Drug Efficacy in Patients with Alzheimer's Disease

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1 site
NCT06650969Recruiting

China Diabetes Cognitive Dysfunction Early Diagnosis and Intervention Study (China-DECODE Study)

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1 site
NCT07328386N/ARecruiting

Effect of Cervical Lymphaticovenous and Lymph Node-to-Vein Anastomosis in Patients With Intracranial Lymphatic Circulation Disorder

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1 site
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NCT05597124Phase 2Recruiting

Exercise to Improve Brain Health in Older African Americans

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1 site
NCT07169578Phase 3Recruiting

A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

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141 sites
NCT04938349N/ARecruiting

Dual Task Perturbation Training for OAwMCI

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1 site
NCT07142278Phase 1Not yet recruiting

DUVAX: A Phase 1 Alzheimer's Vaccine Study Targeting Amyloid-Beta and Tau

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1 site
NCT03082755Phase 4Recruiting

Nighttime Agitation and Restless Legs Syndrome in People With Alzheimer's Disease

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1 site
NCT06544616Phase 2Active

A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease

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90 sites
Phoenix membership

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NCT06613971Recruiting

Dynamic Light Scattering Ocular Measurement in the Detection of Dementia

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1 site
NCT02994719Recruiting

Gait Analysis in Neurological Disease

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1 site
NCT03434548Recruiting

IMarkHD: in Vivo Longitudinal Imaging of HD Pathology

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1 site
NCT03592563Recruiting

CUHK Brain Health Longitudinal Study

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2 sites
NCT04583215N/AActive

Enhancing Frontal Lobes Plasticity in Mild Cognitive Impairment

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1 site
NCT06840587N/ARecruiting

Connect-Home: Alzheimer's Disease and Related Dementias

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1 site
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NCT03909347N/AActive

PLAN: Dementia Literacy Education and Navigation for Korean Elders With Probable Dementia and Their Caregivers

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2 sites
NCT04715399Recruiting

UPenn Observational Research Repository on Neurodegenerative Disease

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1 site
NCT07347574Not yet recruiting

NeuroCare Community Project: A Community Based Prospective Observational Study for Early Alzheimer's Detection in HK

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1 site
NCT06935578Recruiting

RAre, But Not aLone: a Large Italian Network to Empower the Impervious diaGNostic Pathway of Rare cerEbrovascular Diseases (ALIGNED)

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17 sites
NCT05934188Recruiting

Exploring the Gut-Brain Axis in Ageing and Neurodegeneration

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3 sites
NCT05077618Recruiting

Nalysis of the Periodontal Microbiota in Elderly Subjects With and Without Alzheimer's Disease: a Case Control Study

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1 site
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NCT06898476N/ARecruiting

Silkworm Pupa Powder Improves Dementia.

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1 site
NCT06516588Phase 2Recruiting

tDCS for Post-Stroke Cognitive Impairment

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1 site
NCT06508268Recruiting

Language, Speech and Motor Function in MCI Due to AD and Alzheimer's Disease

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1 site
NCT06027554Phase 2Recruiting

The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults

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1 site
NCT07511868N/ANot yet recruiting

Digital Application for Stroke Health

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7 sites
NCT07128186Recruiting

The Application of an AI-driven Multimodal Predictive Model for Cognitive Impairment in Patients With Type 2 Diabetes Mellitus

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21 sites
Phoenix membership

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NCT06803797N/AActive

BCT Intervention For Walking Habit Among Caregivers of People With AD/ADRD

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1 site
NCT07409597N/ANot yet recruiting

Autobiographical Memory, Future Thought, and Eye Movements in Huntington's Disease

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1 site
NCT05537610N/ARecruiting

Extensions of Resurgence as Choice

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1 site
NCT07122856Not yet recruiting

Predictive Factors for Initial MMSE Score and Rapid Decline in Alzheimer's Disease Patients

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1 site
NCT07230366N/ANot yet recruiting

Clinical Validation of AI-powered Smart Vehicle Assisted Gait Training in Neurodegenerative Disorders

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1 site
NCT07507812N/ANot yet recruiting

Fall Prevention in Mild Cognitive Impairment

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1 site
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NCT07140601Recruiting

Environmental Pollutants and Neurological Disorders

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1 site
NCT06330155Not yet recruiting

A Genetic Study for Alzheimer Dementia: Case-control Study

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NCT06731049N/ARecruiting

Comparison of the Effectiveness of Treadmill-Based Walking and Dual-Task Walking Training in Alzheimer's Disease

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1 site
NCT05574400Phase 2Active

The Caffeine, Postoperative Delirium, and Change in Outcomes After Surgery (CAPACHINOS-2) Study

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1 site
NCT07225400N/ANot yet recruiting

Designing a Spatial Navigation Intervention Protocol Informed by Region-specific Brain Activation for Mild Cognitive Impairment

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1 site
NCT06996730Phase 2Not yet recruiting

A Study of Donanemab, RG6289, or the Combination of Donanemab and RG6289 in Presenilin 1 (PSEN1) E280A Mutation Carriers for the Treatment of Autosomal-Dominant Alzheimer's Disease

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1 site
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NCT07324330N/ARecruiting

Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity

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1 site
NCT06304129N/ANot yet recruiting

Diagnostic Performance of Plasma Biomarkers of Alzheimer's Disease Compared With CSF Markers

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1 site
NCT06747637N/ARecruiting

Demonstrating the Efficacy of a Spanish-Language Program for Latino Dementia Caregivers

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1 site
NCT06804837N/AActive

Implement and Test Visual Consent Template and Process

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3 sites
NCT07012629Phase 3Recruiting

A EUROpean Randomized Study on Blood-thinners and Cholesterol-lowering Treatments to Prevent Future Vascular Events in People With Covert Brain Infarcts (CBI)

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14 sites
NCT06631742N/ARecruiting

Exergaming Revolution in Dementia

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1 site
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NCT07118137Recruiting

Memory Deterioration in Alzheimer Disease

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1 site
NCT06223360Phase 2Recruiting

A Trial to Evaluate the Safety and Efficacy of Benfotiamine in Patients With Early Alzheimer's Disease (BenfoTeam)

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47 sites
NCT06185010N/ARecruiting

Resistance Training to Individuals for Cognitive Impairment With Dementia

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1 site
NCT06920212N/AActive

Clinical Safety and Efficacy of Fecal Microbiota Transplantation (FMT) in the Treatment of Alzheimer's Disease

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1 site
NCT07409506Recruiting

Assessment of Informal Support Provided by Caregivers at Different Stages of Alzheimer's Disease

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1 site
NCT03924414Phase 4Active

Trial of Parkinson's And Zoledronic Acid

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77 sites
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80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

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NCT07545577N/ANot yet recruiting

Randomized Controlld Trial of Dementia Education Resources for Action

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NCT07099053Recruiting

Amyloid PET Imaging in the Baltimore Longitudinal Study of Aging

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1 site
NCT07021040N/ARecruiting

Olfactory Biopsies

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1 site
NCT03799991N/ARecruiting

Vestibular Therapy in Alzheimer's Disease

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1 site
NCT06827678Recruiting

Establishment of the Chinese Preclinical Alzheimer's Disease Study With Multiple Neuroimaging

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1 site
NCT07531082N/ANot yet recruiting

Effects of a Salutogenic Strength-based Social Robot-assisted Intervention on the Depressive Symptoms and Sense of Coherence of Family Caregivers of Persons With Dementia

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Phoenix membership

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NCT07545473N/ARecruiting

Retinal Hyperspectral Imaging in Neurodegenerative Diseases

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1 site
NCT07324161N/ARecruiting

Efficacy and Safety of Transcranial Magnetic Stimulation in Treatment of Alzheimer's Disease

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1 site
NCT04740580Early Phase 1Recruiting

Glutathione, Brain Metabolism and Inflammation in Alzheimer's Disease

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1 site
NCT05023564Recruiting

PUMCH Dementia Longitudinal Cohort Study

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1 site
NCT06667817N/ARecruiting

Exercise From Afar: Progressing At Risk Individuals to Independent Exercise

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1 site
NCT02855476Recruiting

HDClarity: a Multi-site Cerebrospinal Fluid Collection Initiative to Facilitate Therapeutic Development for Huntington's Disease

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40 sites
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NCT04517552Active

Investigation of Inflammation Using [C-11]-CS1P1

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1 site
NCT05460468N/ARecruiting

Neuromodulation of Memory in Aging

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1 site
NCT05826548N/ARecruiting

Financial Abilities in Neurological Diseases. Development of a Telerehabilitation Program: FINAGE

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1 site
NCT06245616N/AActive

Attenuation of Postprandial Inflammatory Processes in Alzheimer's Disease Patients by Consumption of Pomace Oil

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1 site
NCT07115238Phase 3Recruiting

Analysis of 18F-XTR006 PET Imaging in Cognitively Normal Subjects, and Patients With MCI and AD

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1 site
NCT07334392N/ARecruiting

Impact of a Multicomponent Exercise Program on Cognitive and Functional Outcomes in Patients With Mild Cognitive Impairment

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1 site
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NCT06781333Phase 2Recruiting

Human Mesenchymal Stem Cells (hMSC) in Behavioral Problems Due to Alzheimer's Disease.

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1 site
NCT07372066N/ARecruiting

Cognitive Stimulation Therapy Group for Residential Home Residents With Dementia and Mild Cognitive Impairment

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1 site
NCT07499570N/ARecruiting

Multi-modal Large Language Model-Empowered Talk Therapy for Older Adults With ADRD

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1 site
NCT05313529N/AActive

LIGHT-MCI Trial: GLP-1 Agonist, SGLT2 Inhibitor, and DPP-4 Inhibitor for MCI Remission in Type 2 Diabetes

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5 sites
NCT07066137N/AActive

Motor Learning in Health and Movement Disorders: Role of Physical Activity and Advanced Devices

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1 site
NCT06444568N/ARecruiting

Modified Ketogenic Diet in Amnestic Mild Cognitive Impairments

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1 site
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NCT03162081Active

Medication Misuse and Dependence Among Elderly

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1 site
NCT06983769N/ARecruiting

CPAP vs MAD for OSA in Patients With Cognitive Impairment. A Randomized Clinical Trial

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1 site
NCT06761729N/ANot yet recruiting

The Ketogenic Diet in the Treatment of Behavioral Variant Frontotemporal Dementia

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NCT07097675N/ANot yet recruiting

The Change in Psychoemotional State of Individuals With Dementia Syndrome Applying Art Therapy

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NCT06362629N/ARecruiting

AI App for Management of Atopic Dermatitis

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1 site
NCT07552896Not yet recruiting

Effect of Daily Screen Time on Postoperative Emergence Delirium in Children Aged 2-11 Years

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1 site
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NCT05507905N/AActive

Effects of Dance and Music Appreciation on Brain Health and Fitness in People at Risk for Alzheimer's Disease

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1 site
NCT06120361Recruiting

The Swedish BioFINDER - Primary Care Study

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1 site
NCT06241287N/ARecruiting

BELIDE: Better Living With Non-memory-led Dementia

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1 site
NCT06948929N/ARecruiting

Synbiotic Formula (SCV09) in Alzheimer's Disease Patients

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1 site
NCT05661084N/ARecruiting

Non-invasive Brain Stimulation for Cognitive and Motor Dysfunction in Dementia

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1 site
NCT06338215N/ARecruiting

Advice of Moderate Drinking Pattern Versus Advice on Abstention on Major Disease and Mortality

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1 site
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NCT07139678Not yet recruiting

Safe Use of Mobility Aids Checklist (SUMAC) for 4-wheeled Walker Use in Turkish Geriatric Population

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NCT04033510Active

Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)

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1 site
NCT05688618N/ARecruiting

Effect of the Administration of a Symbiotic (E. Faecium and Agave Inulin) on Mild Cognitive Impairment in Older Adults

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1 site
NCT05282550Phase 2Recruiting

Targeting Cognition in Early Alzheimer's Disease by Improving Sleep With Trazodone

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1 site
NCT04639050Phase 1Active

Brainshuttle AD: A Multiple Ascending Dose Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7126209 Following Intravenous Infusion in Participants With Prodromal or Mild to Moderate Alzheimer's Disease

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41 sites
NCT03135327N/ARecruiting

Clinical Applications of Advanced Ophthalmic Imaging

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1 site
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NCT05184569Phase 1Recruiting

Veri-T: A Trial of Verdiperstat in Patients With svPPA Due to TDP-43 Pathology

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5 sites
NCT06874231Recruiting

Brain Connectivity Marker for Alzheimer's Disease

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1 site
NCT06148051Recruiting

AusCADASIL: An Australian Cohort of CADASIL

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5 sites
NCT06102486Recruiting

MCI Speech in Noise

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1 site
NCT06005935Active

Environmental and Reproductive Health Risk for Lewy Body Dementia

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1 site
NCT06880510N/ARecruiting

The Locus Coeruleus, Norepinephrine and Cognitive Aging

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1 site
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NCT05399888Phase 2Active

A Study to Learn About the Safety of BIIB080 Injections and Whether They Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age

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138 sites
NCT07526480N/ANot yet recruiting

Improving Dementia Care in Primary Practice

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NCT06528951N/AActive

Impact of Resistance Training Volume on Cognitive Function and Physical Performance in Cognitively Impaired Individuals

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1 site
NCT06703541Recruiting

ADRC Clinical Cohort (Alzheimer's Disease)

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1 site
NCT07135245Phase 2Not yet recruiting

Improved Treatment and Monitoring of Alzheimer's Disease

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NCT07138677N/ARecruiting

Safty and Efficacy of MCI Network Guided TMS for Early Alzheimer's Disease: A Randomized, Double-blind Trial

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1 site
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NCT06757569N/ARecruiting

Radialis PET Imager for the Assessment of Neuritic Amyloid Plaque Burden

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1 site
NCT06881277N/ANot yet recruiting

Effectiveness of a Smartphone App (PRIMI) to Promote Healthy Diet and Physical Activity After Pregnancy in Migrant Women

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NCT05738486Phase 3Active

A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease (TRAILBLAZER-ALZ 6)

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49 sites
NCT05245903RecruitingAPOE4-explicit

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

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1 site
NCT03382223Active

Panel Study Investigating Status of Cognitively Impaired Elderly in Singapore

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9 sites
NCT07105800N/ARecruiting

Dance Intervention to Improve Executive Function and Physical Performance in Older Adults With Cognitive Impairment

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1 site
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NCT04829500N/AActive

Effectiveness and Implementation of Montessori Approaches in Person-Centered Care Within VA

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1 site
NCT06739967Recruiting

Speech and Language Interventions for Italian People With PPA

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2 sites
NCT07563244N/ARecruiting

Computer-assisted Cognitive Stimulation Treatment for Delirium

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1 site
NCT06677632Not yet recruiting

Targeting zDHHC Enzymes to Counteract Alzheimer's Disease

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1 site
NCT07333898Not yet recruiting

Digital Measurements of Motor and Voice Functions in FTD

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NCT04337255N/AActive

Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) Diet in Stroke Patients Patients

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1 site
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NCT06872658Not yet recruiting

Study to Detect Dendritic Cell Recruitment in Human Retina

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NCT07224347Active

Aspirin in Reducing Events in the Elderly-Extension (ASPREE-XT)

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36 sites
NCT07103434N/ANot yet recruiting

VR-based Mindfulness for Dementia Caregivers in the Home Environment (Mind-body Interventions)

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NCT06601933Phase 2Recruiting

Cognitive Training and Neuroplasticity in Mild Cognitive Impairment: COGIT-2 Trial

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4 sites
NCT05846984N/AActive

Learning Skills Together Family Caregiver Complex Intervention

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1 site
NCT07286812Not yet recruiting

Digital Technology Combined With Blood Marker Screening and Diagnosis for Community Populations Based on Classification Theory: an Integrated Study

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1 site
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NCT04305600Active

Bringing to Light the Risk Factors And Incidence of Neuropsychological Dysfunction in ICU Survivors, 2nd Study

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2 sites
NCT03653156RecruitingAPOE4-explicit

China Cognition and Aging Study

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65 sites
NCT06516965Phase 3Active

A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)

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119 sites
NCT07347912N/AActive

Group-based Resistance Training for Adults With Down Syndrome

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1 site
NCT05405075Recruiting

Arizona Alzheimer's Disease Research Center (ADRC)

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5 sites
NCT04610944N/AActive

Changing Talk Online Training (CHATO) National Trial

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1 site
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NCT06834893N/ANot yet recruiting

Assessing the Effects of Cool Roofs on Indoor Environments and Health in Colima, Mexico

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1 site
NCT04935372Active

β-AARC: Cohort Study for the Identification of Blood-based Biomarkers in a Population With Subjective Cognitive Decline

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1 site
NCT04793776N/ARecruiting

Manage Emotions to Reduce Aggression (MERA)

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2 sites
NCT06634368N/ARecruiting

Pilot Study of Hospital GamePlan4Care

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1 site
NCT05527405N/AActive

Efficacy of Caregiver Training Program in Enhancing Caregiver and Patient Outcomes

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1 site
NCT07227961Recruiting

PROMIS and Mobility Evaluation in Sarcoma Patients

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4 sites
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NCT07457125Phase 1Not yet recruiting

The Effect of CB-Exo-A600 in Mild to Moderate Alzheimer's Disease

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1 site
NCT05794061Recruiting

Advances in Neuropsychological Diagnostics

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1 site
NCT07214727Phase 1Recruiting

A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease

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11 sites
NCT07081750N/ANot yet recruiting

Dyadic Tailored Home-Based Activity Program for Mild-to-Moderate Dementia Patients Post-Discharge

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NCT07456462N/ANot yet recruitingAPOE4-explicit

Making Antibody Treatments More Effective in Early Alzheimer's Disease Using 3Tesla Magnetica Resonance

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1 site
NCT07127510Recruiting

Brain NAD in Alzheimer's Disease

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1 site
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80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

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NCT06093126Phase 4Recruiting

Lemborexant for Insomnia in a Patient With Dementia: An N-of-1 Trial

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1 site
NCT06521918Recruiting

Combined Artificial Intelligence and Mobile Application for Remote Infant Motor Screening: Development and Validation

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1 site
NCT02014246Recruiting

Genetic Characterization of Movement Disorders and Dementias

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1 site
NCT07434479N/ARecruiting

A Virtual Reality Mindfulness Application for Aggression in Schizophrenia

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2 sites
NCT06143488N/ARecruiting

Endovascular Therapy Versus Best Medical Treatment for Acute Large Vessel Occlusion Stroke With Low NIHSS

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1 site
NCT07549074N/ANot yet recruiting

Multicomponent Intervention to Improve Cognitive Abilities in Older Adults With Mild Cognitive Impairment

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1 site
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NCT07503743Active

Biology-Driven Cognitive Profiling in Huntington's Disease

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1 site
NCT06880406N/ARecruiting

Mitochondrial Function and Metabolomic Profile in Alzheimer's Disease and Related Dementias

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1 site
NCT06411561N/ARecruiting

A Multi-Modal Combination Intervention to Promote Cognitive Function in Older Intensive Care Unit Survivors

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1 site
NCT06268886Phase 2Active

Study to Evaluate the Efficacy, Safety, and Tolerability of an Anti-MTBR Tau Monoclonal Antibody (BMS-986446) in Participants With Early Alzheimer's Disease

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176 sites
NCT07461168N/ANot yet recruiting

Penn State Emergency Medicine CarES: Care-partner Evaluation and Sourcing in the Emergency Department

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1 site
NCT06032351N/ARecruiting

Construction and Validation of Dementia Care Management Competency

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1 site
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NCT05081596N/ARecruiting

A Primary Care-Based Psychosocial Intervention To Improve Cognitive & Depression Outcomes in Older Adults With MCI & Early Stage AD

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1 site
NCT07288463N/ANot yet recruitingAPOE4-explicit

Hearing Loss and Genetic Risks for Alzheimer's Disease and Related Dementia

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1 site
NCT06784830N/ARecruiting

Nursing Interventions for Alzheimer's Patients During PET/CT Imaging

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1 site
NCT07212699N/ARecruiting

Development of an Outcome Score for Patients With Knee Osteoarthritis and Knee Joint Endoprosthesis Using an App

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1 site
NCT03705104N/AActive

Living Well with Chronic Pain

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1 site
NCT06058234Recruiting

Medicare Anti-Aβ mAb Coverage With Evidence Development (CED) Study

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1 site
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NCT05470816Phase 3Active

Tranexamic Acid to Reduce Delirium After Gastrointestinal Surgery: the TRIGS-D Trial

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1 site
NCT07496021N/ARecruiting

Safety and Efficacy of L. Lactis CKDB001 in Subjects With Early Alzheimer's Disease

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2 sites
NCT06096090Phase 2Recruiting

Phase II Clinical Trial of Interleukin-2 in AD

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1 site
NCT05541627Phase 1Active

A Study to Evaluate AB-1001 Striatal Administration in Adults With Early Manifest Huntington's Disease

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1 site
NCT06837272Recruiting

A Longitudinal Study to Explore the Impact of Gut Microbiome on Brain Health in Alzheimer's Disease

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1 site
NCT05529277Active

Implementing Dementia Care Management Into Routine Care in the Region Siegen-Wittgenstein

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6 sites
Phoenix membership

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80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

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NCT03894254N/ARecruiting

Predictive Factors of Autonomy Loss in Real-life Cohort

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5 sites
NCT05655403N/ARecruiting

Effects of Step Training in Older Adults with Mild Dementia

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1 site
NCT03772977N/AActive

The Brain Health Champion Study

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1 site
NCT04396873Phase 1Recruiting

PET Imaging of Cyclooxygenases in Neurodegenerative Brain Disease

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1 site
NCT07058688Phase 2Recruiting

A Study of NTRX-07 in Participants With Alzheimer's Disease

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6 sites
NCT07160959N/ANot yet recruiting

Physical Exercise to Prevent Mild-cognitive Impairment in Patients With Kidney Disfunctions

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6 sites
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NCT06664229N/ARecruiting

Development of Pressure Sensor Based Dementia and Fall Prevention Program for Older Adults

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1 site
NCT07040904N/ARecruiting

Mindfulness to Enhance Cognitive Health in Latinx Older Adults

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1 site
NCT06417749N/ANot yet recruiting

MIND Diet and Cognitive Function in Middle-aged and Older Adults

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1 site
NCT05886114N/ARecruiting

A Multi-domain Lifestyle Intervention Among Aged Community-residents in Zhejiang, China

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1 site
NCT07306598Recruiting

[18F]NIDF PET Imaging in Tau-related Diseases

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2 sites
NCT05413655Phase 2Recruiting

A Study of Oral EX039 in Subjects with Mild Alzheimer's Disease

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1 site
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80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

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NCT06291909N/AActive

Small Steps Towards Improving Activity and Sleep Habits to Decrease the Risk of Dementia

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1 site
NCT06338904N/ARecruiting

Brief Problem-solving Intervention in Different Formats for the Prevention of Suicide in Adults Over 50

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1 site
NCT07410052N/ANot yet recruiting

Microbiome-Targeted Enhancement of Neurocognition With Probiotics-Riboflavin Combination

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NCT05522647Recruiting

Detection of Risk Behaviors: Pilot Observational Study With Bedridden and Agitated Patients.

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1 site
NCT07101380N/ARecruiting

Feasibility Study of 'SuperBrain BOOM' for Mild Cognitive Impairment Patients

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4 sites
NCT05206305N/AActive

Sensory-Evoked Cortical Gamma Oscillation

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site
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80% of APOE4 carriers don't realize they're disqualified until the screening call. Phoenix matches you in 60 seconds.

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NCT04713982Phase 2Active

Impact of Deutetrabenazine on Functional Speech and Gait Dynamics in Huntington Disease

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1 site
NCT06432166Phase 1Not yet recruiting

2-Hydroxybenzylamine (2-HOBA) Study in Early Alzheimer's Patients

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1 site
NCT07109999Recruiting

Biomarker-based Alzheimer's Disease Cohort Study (BASIC)

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1 site
NCT06876857Recruiting

University of Central Florida CereBank

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1 site
NCT06792877N/ARecruiting

Mindfulness for Cognition in Early-stage Alzheimer's Disease

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1 site
NCT07059871N/ARecruiting

A Study of Silkworm Pupa Powder Intervention in the Nutritional Status of Patients With Alzheimer's Disease.

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1 site
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NCT07182019N/ANot yet recruiting

Connecting Today to Combat Social Isolation and Loneliness

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NCT06528964Recruiting

Proteinopathies Expression in Skin of Neurodegenerative Disorders

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1 site
NCT07005895Recruiting

Feasibility of Using the Gatorade Sports Science Institute (GSSI) Labs App for Hydration Related Outcomes

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1 site
NCT07061340N/ANot yet recruiting

The Effect of Therapeutic Touch on Agitation, Pain, and Cortisol Levels in Intensive Care Patients

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1 site
NCT07321821N/AActive

Fermented Garlic Lettuce Powder and Cognitive Function in Adults With Mild Cognitive Impairment

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1 site
NCT05950607N/ARecruiting

Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

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1 site
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NCT07448909Not yet recruiting

Cognitive-Frailty Gait Biomechanics for Early Dementia Detection

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1 site
NCT06058611N/ARecruiting

Effects of a Computerised Cognitive Stimulation Versus Stimulating Leisure Activities

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1 site
NCT07473492Not yet recruiting

Assessment of Malnutrition in Hospitalized Patients: a Quasi Study

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NCT04946916N/ARecruiting

Neurofilament Light Chains and Cognitive Impairment in Chronic Psychiatric Disease

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2 sites
NCT05896332Phase 1Active

rTMS in Older Adults With MCI and AUD

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2 sites
NCT04458207N/AActive

Cognitive Changes and Neural Correlates After Rehabilitation of Masticatory Function in Elderly -an Intervention Study

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2 sites
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NCT04908358N/AActive

The Wandering Nerve: Gateway to Boost Alzheimer's Disease Related Cognitive Performance

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1 site
NCT06437132Recruiting

Decoding Death and Dying in People With Dementia by Digital Thanotyping

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1 site
NCT07239609Phase 1Not yet recruiting

ACT for Individuals With MNCD and Their Care Partners

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NCT06933095N/ARecruiting

Optimizing CNS DHA Delivery in Elderly Adults at Risk for Dementia

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1 site
NCT05890313N/ANot yet recruiting

Improving the Referral of Patients With Suspected Cognitive Impairment and Early Dementia

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1 site
NCT06611202N/ANot yet recruiting

Enhancing Mobility and Mental Health in Dementia Patients

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1 site
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NCT05277129Recruiting

The Immune Response to Stroke

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1 site
NCT04997642Recruiting

Parkinson's Disease and Movement Disorders Clinical Database

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1 site
NCT03098459Active

Illuminating Neuropsychological Dysfunction and Systemic Inflammatory Mechanisms Gleaned After Hospitalization in Trauma-ICU Study

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1 site
NCT07417891N/ANot yet recruiting

Ketogenic Diet to Reduce Osteoarthritis Pain in MCI

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1 site
NCT06412185Phase 1Recruiting

Single Dose Escalation Study of CM383 in Healthy Volunteers

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1 site
NCT07496918Phase 2Recruiting

Brain Effects of Gamma Frequency Sensory Stimulation (40Hz Light, Sound and Other Devices)

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1 site
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NCT06403345N/ARecruiting

A Feasiblity Study of Green Activity Program for People Living With Memory Challenges

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1 site
NCT05575271N/ANot yet recruiting

Implantable Vagus Nerve Stimulation Modulation of Coeruleus-Norepinephrine Network for Mild-Moderate AD Patients

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1 site
NCT05649800Recruiting

Vascular mEchanisms in, Stroke, dePression, dementiA, and deliRum: The VESPAR Project

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2 sites
NCT07411365N/ANot yet recruiting

Dual-task Cognitive-motor Telerehabilitation in Persons With PD-MCI

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1 site
NCT05708001N/ARecruiting

Improvement of Memory in Mild Cognitive Impairment

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1 site
NCT05796037Not yet recruiting

An Observational Study of Patients Living With Chronic Neurological Diseases

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NCT06854731N/ARecruiting

Preventing Falls in Older Adults With Cognitive Frailty

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1 site
NCT06868030Not yet recruiting

Efficacy and Safety of Conventional Symptomatic Drugs Combined with Lencanizumab in the Treatment of Early Alzheimer's Disease: a Multicenter, Prospective, Observational Study

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NCT05421728N/AActive

Effectiveness of Engaging in Advance Care Planning Talks (ENACT) Group Visits in Primary Care for Older Adults With and Without Alzheimer's Disease

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8 sites
NCT07361601Not yet recruiting

Implementation of AIP Services for Older Adults With AD

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1 site
NCT06357195Active

DIAMOND-Lewy Guidelines for Antipsychotic Use in Older Patients

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1 site
NCT03657745Recruiting

Alzheimer's Disease Treatment With Combination of 40Hz Light and Cognitive Therapy

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1 site
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NCT05642429Phase 1Active

Study of AV-1959D, an Amyloid Beta Vaccine

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6 sites
NCT04692441N/ARecruiting

Apolipoprotein E (APOE) Genotype Effects on Triglycerides and Blood Flow in the Human Brain

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1 site
NCT06933667N/ARecruiting

Kimel Family Centre for Brain Health and Wellness

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1 site
NCT07425769N/ANot yet recruiting

Adapting RDAD for DS

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1 site
NCT05867641N/ARecruiting

VR&R: Providing Caregiver Respite by Managing BPSDs and Improving QoL in People with Dementia Using Immersive VR-Therapy

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7 sites
NCT03614962N/ARecruiting

Warmth and Transcutaneous Electrical Nerve Stimulation (TENS) in Improving Cognitive Functions in People with Dementia

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1 site
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NCT05820919N/ARecruiting

Enhancing Sleep Quality for Nursing Home Residents With Dementia - R33 Phase

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3 sites
NCT06672367N/ARecruiting

Effects of Balance Training with and Without Gaze Stability Exercises on Cognitive Function Balance and Dynamic Postural Stability in Older Adults with Mild Cognitive Impairment

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1 site
NCT03846492N/AActive

Targeting Brain Physiology to Treat Neuropsychiatric Symptoms of Dementia Using TMS-EEG and tDCS

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1 site
NCT06734286N/ARecruiting

Working Memory Training in Patients with Mild Cognitive Impairment

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1 site
NCT07086261N/AActive

Using SRT to Improve The Drinking Problem Behavior of Elderly People With Dementia During The Care of Day Care

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1 site
NCT06836180Early Phase 1Not yet recruiting

An Exploratory Study of Near-infrared Light Therapy for Mild to Moderate Alzheimer's Disease

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1 site
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NCT06930742N/ANot yet recruiting

Mindfulness-Enhanced Dual-Task Training in PD-MCI

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1 site
NCT06989242N/ANot yet recruiting

Yoga-based, Movement Therapy Device as Noninvasive Glymphatic Clearance Augmentation in Alzheimer's Disease.

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3 sites
NCT04132362Recruiting

Benefits of Personalised Music in Dementia - a Feasibility Study

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1 site
NCT06922188Recruiting

Development of Measures to Screen for Financial Hardship in Alzheimer's Disease and Dementia

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1 site
NCT05356702N/AActive

The Brain Health Study: A Pragmatic, Patient-Centered Trial

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5 sites
NCT07240805Not yet recruiting

Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy Bodies

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2 sites
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NCT05463731Phase 3Active

A Study of Remternetug (LY3372993) in Participants With Alzheimer's Disease (TRAILRUNNER-ALZ 1)

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76 sites
NCT07099040N/ANot yet recruiting

Community-based Multi-domain Intervention to Detect and Delay Cognitive Decline in Community-dwelling Older Adults: A Pilot Study

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NCT07252440Phase 2Recruiting

A Study to Evaluate the Efficacy and Safety of TTYP01 Tablets in Early Symptomatic Alzheimer's Disease

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1 site
NCT03887455Phase 3ActiveAPOE4-explicit

A Study to Confirm Safety and Efficacy of Lecanemab in Participants With Early Alzheimer's Disease

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247 sites
NCT06679296Recruiting

Study on Aging and Cognitive Impairment in China

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1 site
NCT03556280N/AActive

Multi-Center Study of Sensory Stimulation to Improve Brain Function

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5 sites
Phoenix membership

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NCT06559813N/ANot yet recruiting

Pilot Study of Parent Training With Role-plays in Virtual Reality for Parents of Children With Behavior Problems

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NCT05643144N/ARecruiting

Enhancing Shared Decision-making to Guide Care for People With Dementia and Diabetes

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1 site
NCT07146412N/ARecruiting

Impact of a Multimodal Lifestyle Intervention on Dementia Risk Factors and Attitude Related to Dementia Risk: A Logistical Pilot Study

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1 site
NCT06419101Recruiting

Exploring the Diagnostic Biomarkers of Cognitive Disorders in China

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1 site
NCT04246437Phase 1Recruiting

[18F]F-DOPA Imaging in Patients With Autonomic Failure

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1 site
NCT07031167N/ANot yet recruiting

The COMFORTage Project at Ace Alzheimer Center Barcelona

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1 site
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NCT06871488Phase 4Recruiting

Predictors of Improvements in Irritability and Aggression in Children With ADHD Treated With CNS Stimulants

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1 site
NCT06052163Phase 2Recruiting

Bumetanide in Patients With Alzheimer's Disease

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1 site
NCT06351800N/ANot yet recruiting

The PredictPlusPrevent Study

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NCT07361887N/ARecruiting

Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles.

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1 site
NCT06306144N/ANot yet recruiting

Early-phase Telecare Programs for Minor Stroke

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3 sites
NCT07012993Phase 2Recruiting

Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol

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1 site
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NCT07392944N/ARecruiting

Multicomponent Exercise Program on Physical Function, Cognition and Falls Risk Among Older Adults Living in Nursing Homes (MOVE4CARE)

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1 site
NCT06896812N/ANot yet recruiting

A Pilot Study on App-based Treatment Combining Physical Exercise, Graded Activity, and Pain Journaling for Patients with Spinal Complaints

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NCT05795634N/ARecruiting

Cognitive Vulnerability to Stress in Individuals at Risk for Alzheimer's Disease

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1 site
NCT06418971N/ARecruiting

Testing & Refinement of CarePair: An Assessment and Referral Platform to Support Family Caregivers of Alzheimer's Disease and Related Dementias.

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1 site
NCT07452939N/ARecruiting

Prefrontal Theta Burst Stimulation to Improve Cognitive Impairment After ICU Delirium

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1 site
NCT05372159Recruiting

Vanderbilt Memory and Aging Project

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1 site
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NCT06947941Phase 3Recruiting

A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)

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20 sites
NCT05691569N/ARecruiting

Efficacy of Doll Therapy in the Dementia in Acute Geriatric Inpatients

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1 site
NCT07209124N/AActive

Increasing Engagement and Positive Emotional Behavior of Older Adults With Mild-Moderate Dementia With the Use of Motion-Based Technology and Meaningful Activities

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1 site
NCT05808153N/ARecruiting

Innovative Imaging and Cognitive BIOmarkers to Predict Huntington's Disease Progression

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1 site
NCT05452031N/ARecruiting

A Dyadic Sleep Health Approach for Persons With Alzheimer's Disease and Caregivers

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3 sites
NCT07241156N/ANot yet recruiting

Creative Drama on Gender Role Stress, Attitudes Toward Violence Against Women, and Aggression

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Phoenix membership

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NCT06772194Recruiting

Taiwan Post-Stroke Disability Study

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1 site
NCT07002996N/ARecruiting

Spatial Memory Training and Cognitive Function

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1 site
NCT07248345N/ANot yet recruiting

Virtual Reality Intervention for Family Caregivers of Persons Living With Dementia

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NCT06224205N/ARecruiting

Digital Detection of Dementia (D Cubed) Studies: D3

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1 site
NCT05997030N/ARecruiting

Low-Intensity Focused Ultrasound (LIFU) Neuromodulation

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1 site
NCT06474013N/ANot yet recruitingAPOE4-explicit

A Clinical Trial to Evaluate the Initial Safety and Efficacy of Repetitive BBB (Blood Brain Barrier) Disruption Using High Intensity Focused Ultrasound 'ExAblate 4000 Type 2.1' in Patients With Alzheimer's Disease

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Phoenix membership

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NCT06889818Recruiting

Korean Joint Registry for Alzheimer's Treatment and Diagnostics (JOY-ALZ)

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3 sites
NCT06014424Phase 2Recruiting

Cannabidiol Medication Intervention Trial

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5 sites
NCT05361382Phase 1Active

Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease

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9 sites
NCT06209515Active

Sociodemographic Factors and Criminal Behaviour Preceding Neurodegenerative Disease - Retrospective Register Study

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1 site
NCT05395624Phase 1Recruiting

Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers

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3 sites
NCT02649985Phase 1Recruiting

PET Brain Imaging in Multiple Sclerosis, Alzheimer's Disease, and Other Neurological and Neuropsychiatric Diseases

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1 site
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NCT07218081Phase 1Recruiting

A Trial to Test Intermittent Deep Brain Stimulation of Nucleus Basalis of Meynert to Treat Alzheimers.

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1 site
NCT05686551Phase 2Active

GENERATION HD2. A Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen Compared With Placebo in Participants With Prodromal and Early Manifest Huntington's Disease

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70 sites
NCT05903573N/ARecruiting

Training Response Artificial Intelligence Network (TRAIN)

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1 site
NCT06089096Recruiting

Sleep Apnea and Cognitive Function in Subjects With Subjective or Mild Cognitive Impairment

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1 site
NCT07034222Phase 4Active

12-Month Real-World Safety & Efficacy of Lecanemab in Early Alzheimer's Disease

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1 site
NCT07290387N/ARecruiting

Tele-Savvy for Latino Caregivers

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1 site
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NCT06416371Recruiting

Retinal Vessel Leakage in Cerebral Small Vessel Disease

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1 site
NCT06877312N/ARecruiting

Longitudinal Study to Investigate Different Transcranial Electrical Stimulation

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1 site
NCT05619263N/ARecruiting

Emergency Preparedness for Caregivers of Persons With Dementia: Disaster PrepWise

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1 site
NCT05534607N/ARecruiting

Natives Engaged in Alzheimers Research - 'Ike Kupuna

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3 sites
NCT07488195N/ANot yet recruiting

A Study Of Phototherapy In Patients With Dementia To Improve BPSD

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1 site
NCT06147999N/ARecruiting

Impact of a Biophoton Therapy on Patients With Brain Disorders

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1 site
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NCT06725706Recruiting

Beta Amyloid PET/CT in Various Aβ-Related Disease

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
3 sites
NCT06608316N/ARecruiting

Intermittent Theta-burst Stimulation for Mild Cognitive Impairment

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2 sites
NCT05014971N/ARecruiting

Telehealth in Lewy Body Dementia

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1 site
NCT07251738Not yet recruiting

Understanding the Lived Experience and Bereavement of Caregivers of People With Alzheimer's Disease

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NCT07185867N/ANot yet recruiting

Prevention of ANxiety and Depression Over Risk Assessment

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1 site
NCT05004987Phase 4Recruiting

Aβ Dynamics in LLMD

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2 sites
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NCT05060614Recruiting

Analyses of Cerebrospinalfluid in Patients With Delirium

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1 site
NCT07222280N/ARecruiting

Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy

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6 sites
NCT07367880Not yet recruiting

The Monument Test : A New Tool for Assessing the Ability to Name and Identify Unique Entities. (TeDIMO)

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NCT07075770N/ARecruiting

Novel Personalized Non Invasive Combined Magnetic and Electrical Stimulation of the DMN in Mild AD Patients

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2 sites
NCT06507254N/ARecruiting

Polyphenols and Cognitive Decline

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1 site
NCT03638583Recruiting

Alzheimer Prevention Trials (APT) Webstudy

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1 site
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NCT07093684Active

Dementia and Kidney Disease: Epidemiological Approaches to Risk Factors and Treatment Strategies

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1 site
NCT06237218N/ARecruiting

Effects of the COTID (Community Occupational Therapist in Dementia) Program and Usual Occupational Therapy Care on Recurrence of Falls at 12 Months in Elderly People With Neurocognitive Disorders Who Had Been Hospitalized for Falls, After Their Return Home

Eligibility — Phoenix members see ✓ likely eligible / ✗ excluded based on their profile
1 site

APOE4 Trial Pipeline

Where the trials sit in the development pipeline. Higher bars = more research underway.

6
Early P1
Safety in healthy volunteers
26
Phase 1
Safety + dose-finding
37
Phase 2
Efficacy signal
17
Phase 3
Pivotal — FDA-grade evidence
10
Phase 4
Post-market surveillance

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