Turn APOE4 risk into a plan you can trust.
One loop, four steps. It gets sharper every time you or anyone else runs it.
Four evidence sources, ranked into one shortlist for your genotype, with the uncertainty left visible.
One sequenced protocol, about 90 days, each step aimed at a single number on your panel.
Bloods re-drawn against your own baseline. Your numbers, never an average.
Phoenix AI learns from 684+ carriers running experiments right now, and hands what it learns back to you.
Every result re-enters the loop: yours, and 684+ other carriers’ running right now.
What may be worth trying, ranked.
Four evidence sources, compared against each other, so a promising idea rises to the top, and the uncertainty stays visible instead of getting rounded off.
- PubMedPeer-reviewed evidence
- Clinical trialsWhat's being tested now
- APOE4 researchFindings specific to your genes
- Other APOE4 carriersPatterns across the community
One protocol, fully recorded.
Run the interventions your plan needs. Record the timing, dose, adherence, and target for each one, so every measurement has the context needed to identify what is helping.
- SupplementsTargets your ranked biomarkersNow
- MovementBuilds toward your VO2 max
- SleepSteadies your HRV and recovery
- NutritionShapes your metabolic markers
Trained on evidence. Updated every week. Honest about what it doesn't know yet.
Phoenix AI is trained specifically on Phoenix member research, published APOE4 literature, and clinical trials — the same evidence sources and Know/Act/Proof/Together loop this page walks through.
Weekly refresh
The evidence base is updated weekly as research and trial information change. New does not automatically mean conclusive.
Uncertainty and limits
Phoenix shows caveats and what is still unknown. It helps members identify what may be worth testing and measure their own trends; it does not guarantee a result or replace clinician judgment.
Five members. Five different stacks. One thing in common.
Each lowered LDL-C on a stack that looks nothing like the others. Phoenix AI reads across all five and surfaces the one intervention they share.
You want to lower fasting insulin. Your twins already did.
Phoenix matches you to members who share your profile, then ranks what actually moved their number.
Real members. Real numbers.
Not averages. Named carriers, their own markers, their own words, each one linked to the full interview so you can check it yourself.

I built Phoenix because I needed it. Now we build it together.Read Kevin’s full story

I had to teach my own integrative medicine doctor about APOE4 — I knew more than the neurologists.Watch Robin’s full story

Half the borderline threshold.
Even if they came up with a cure tomorrow, I would do everything I'm doing except the supplements. I love the working out.Watch John’s full story

On supplements targeted by her own genetic testing.
We're the wild variant. We're the tough humans.Watch Gertrude’s full story

Post-menopause, glucose dialled in via CGM.
Do you want to just let your destiny be up to your genes, or do you want to have some agency?Watch Deb’s full story

Ten years in, still building her own protocol.
You can either sit back and do nothing or take action. That's still my attitude.Watch Donna’s full story