For APOE4 carriers

Beat the odds.Outsmart Alzheimer's.

Inside the largest carrier-run APOE4 study in the world. You were probably told nothing can be done. We are proof otherwise.

Join Phoenix

60-day money-back guarantee

Kevin, founder, carries APOE4/4Dr. John Yoder, memberDeb Blum, memberDr. Gertrude Behan, memberDonna Dorans, memberRobin Shwetzer, member

Start from the experience of 654+ APOE4 carriers, never from n=1. Phoenix AI continuously learns from every experiment every member of the community runs, to help you reach the best outcome.

MotivationAccountabilityMomentum

Find your brain health protocol

Recommends what's nextlearning from 654+ APOE4 carriers' experiments

Know which interventions to do

based on your genes and your health profile

You run the experiments

Validate what's working for you

measured by your biomarkers

Learns your biology
Active carriers
654+
150 new join every month
Improve an APOE4 biomarker
89%
Within 3 months · self-reported
Biomarker readings logged
31,000+
Read against APOE4-optimal ranges
As seen in
The signal problem

You can't afford to guess.

All of this “advice” came from a doctor, a podcast or a study. Half of it contradicts the other half. None of it was written for your genotype.

The signal

One protocol.
Tuned to your genotype.
Proved by your bloodwork.

654+carriers running it27markers watched89%see a marker move
The math of APOE4

Your risk isn't fixed.
It's a number you can move.

An APOE 4/4 genotype can push lifetime Alzheimer's risk toward 60 percent. In the FINGER trial, APOE4 carriers got 2.6× more cognitive benefit from multidomain intervention than non-carriers. The gene loads the dice. It doesn't throw them.

Genin 2011Ngandu 2015 (FINGER)Fortea 2024
Lifetime risk by age 85Scale 0–100%
~60%
APOE 4/4 untreated
Measured · Genin 2011
~22%
APOE 4/4 optimized
Modeled · FINGER-style protocol
About 63% lower risk in the optimized scenario
How it works

The more experiments you run, the better Phoenix knows you.

Know what to try, run it, let your bloodwork answer. Every turn through the loop sharpens the next recommendation.

Know

Ranked for your genes, not the average person.

800+ APOE4 papers
1,300 live clinical trials
What worked for carriers like you
Personalized to your health profile

Act

One change at a time, so the answer is clean.

Supplements
Movement
Sleep
Nutrition
First signal around day 30

Proof

Your numbers answer, or they don't.

89%of members improve at least one APOE4 biomarker within 3 months.
27 biomarkers
Together

Stand on the shoulders of 654+ carriers running experiments in parallel. This is how you stop losing time.

654+ APOE4 carriers
You don't run it alone

Matched into a pod of 2–4 carriers, monthly.
Working on the same goals as you.

New pods form on the 1st of every month. Members in a pod stay consistent 3.2x longer than members going it alone.

Pod matching opens monthly
Your pod · this month
Marker discipline. One change at a time.
Sample pod
You
Deb
John
Donna
Deb7:14 a.m.
Held the glucose protocol all month and kept every pound of muscle. It wasn't one supplement. It was staying consistent because you all check in on me.
John9:02 a.m.
That's the push I needed. My p-tau came back 0.09, half the borderline threshold.
What you'll track

The lab said normal. For a 4/4 carrier, it isn't.

27 markers, each read against its medical context rather than one guessed universal range. Here are four of them.

Biomarker
Lab “normal”
Phoenix target
Why the gap matters
ApoB
mg/dL
Lab normal< 90
Phoenix targetBy risk tier
Phoenix uses the reviewed cardiovascular risk tier instead of assigning a target from APOE4 alone.
pTau-217
pg/mL
Lab normalNot run
Phoenix targetBy assay
Nobody orders it. It detects Alzheimer's pathology up to 20 years before symptoms.
Omega-3 Index
%
Lab normal> 4
Phoenix target> 8
APOE4 brains are starved for DHA. The standard floor is half what you need.
hs-CRP
mg/L
Lab normal< 3.0
Phoenix targetRisk context
APOE4 brains run hot. Chronic inflammation multiplies amyloid deposition rather than adding to it.
+ 23 more in the dashboard · every range backed by a peer-reviewed citation
See the full framework
Members

The proof is in their bloodwork.

Three of dozens. Real names, real genotypes, real numbers they moved.

Portrait of Dr. John Yoder
Dr. John Yoder, 68
Retired Physician · Missouri
3/4
0.09
p-tau · half of borderline
Verified by labs

I would have never heard of P-tau testing without this group. Even if none of this prevents Alzheimer’s, I’m living these years healthy and energetic.

Portrait of Robin P. Shwetzer
Robin P. Shwetzer, 62
NBC-HWC Coach · Florida
3/4
5.7 → 5.4
A1C · brain fog gone
Verified by labs

A1C 5.7 to 5.4 on keto-flex, brain fog gone in about a month. Homocysteine 13 to 7 with methylated B vitamins.

Portrait of Donna Dorans
Donna Dorans, 72
Year 10 since diagnosis
4/4
Intact
Cognition · decade with 4/4
Verified by family

It’s like I found my people. The Phoenix app is building something personal that works for me, not a one-size-fits-all protocol.

Three of dozens · full interviews, deltas, and screenshots on the stories page
Browse every story
Do you want to let your destiny be up to your genes, or do you want to have some agency?
— Deb Blum, APOE 4/4Watch Deb's full story
Dr. Kevin Tran, Doctor of Pharmacy, APOE 4/4 carrier, founder of Phoenix
Dr. Kevin Tran
PHARMD · APOE 4/4 · MEMBER 001
Who built this

I carry the same genotype you do.

Phoenix is a one-person, founder-led startup. I spent a decade studying the gene I turned out to carry two copies of. When my result came back, my doctor told me what yours probably did: come back at sixty. I read 800 papers, consulted 40 researchers, and built the protocol I needed. I run it on my own bloodwork, and I ship this product every week.

“I built Phoenix because I needed it. Now we build it together.”

Dr. Kevin Tran, APOE 4/4
Membership

What you actually get, and what it costs.

Two ways in. Cancel in one click, any time. 60 days money back on your first quarter.

Core · Most members
Take control
$69/mo
$828 billed yearly · 2 months free
  • Phoenix AI, trained on APOE4 research and real carrier outcomes
  • Blood test analysis against 27 APOE4-optimal ranges, on any panel you upload
  • AI-validated experiments with a confidence score in 14–30 days
  • Monthly pod matching, 2–4 carriers on your goal
  • Clinical trials engine, APOE4-matched to your profile daily
  • Everything in Ember, including $1,600+/yr in partner perks
Join Core →
Ember · Start smaller
$39/mo
$468 billed yearly

The private community, monthly expert Q&As, the protocol library and the partner perks. No app, no AI, no pods.

Start with Ember
Seven minutes to join. 73% choose yearly.
I just found out. Is it too late?

It is not. APOE4 raises lifetime Alzheimer's risk roughly 4–5× above baseline, but it does not seal fate. The members with the largest biomarker swings are the ones who started in their fifties and sixties. Every year of intervention bends the curve.

I'm joining for a parent, partner, or someone I love.

You belong here too. 88% of members have a family history of Alzheimer's, and for nearly half it was their mother. Caregivers get the same tools, pod, and expert access as every member, alongside people who have walked exactly your road.

I'm not a biohacker.

Neither are most members. The average member is a 58-year-old woman. The app walks you through every step, your pod keeps you honest, and Dr. Tran is one message away.

I'm 3/4, not 4/4. Does this apply?

Yes. Phoenix is built for any APOE4 carrier. The urgency dial is lower; the playbook is the same.

Can I cancel?

Yes, any time, one click, no questions. Plus a 60-day full money-back guarantee on your first quarter.

Start now

Don't wait for symptoms.
Start today.

Every month without tracking is a month of data you can't get back. New pods open monthly.

Seven minutes to join · 60-day money-back guarantee · cancel in one click