NCT07219680 · RECRUITING
Intervention for Communication Quality of Life in Primary Progressive Aphasia
This trial tests a video-based speech therapy program for people with primary progressive aphasia, a condition that gradually affects language, and their communication partners. It measures communication and quality of life. Some people start right away and others wait first. The phase is listed as not applicable, meaning this is a behavioral study, not a drug trial.
Eligibility criteria
Inclusion Criteria for Persons with PPA: * A PPA (Gorno-Tempini et al., 2011) or "PPA-plus" (Mesulam et al., 2001) diagnosis * MMSE score of 15 or higher and must be able to produce single monosyllabic words intelligibly * Must speak English, Spanish or both languages (i.e., bilingual speakers of English or Spanish) * Hearing and vision adequate for participation in teleconference meetings * Must have a study partner available (someone who will commit to attending teleconference sessions, as needed, during assessment and treatment phases) Inclusion criteria for Care Partners: * Partners must express willingness to attend and participate in assessment and treatment sessions, including those targeting dyadic communication goals * Partners must speak English, Spanish or both languages (i.e., bilingual speakers of English or Spanish) * Partner's hearing and vision should be adequate for participation in teleconference meetings The participant and/or study partner must have basic experience using a computer. Exclusion criteria for persons with PPA: * Other central nervous system or medical diagnosis that can account for symptoms * Psychiatric diagnosis that can account for symptoms
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-04-21