NCT07451613 · Phase 1 · RECRUITING
Safety and Tolerability Study of Human Neural Stem Cells for Huntington's Disease
This trial is testing whether implanting human neural stem cells, called hNSC-01, into the brain is safe and tolerable for people with Huntington's disease. It is a Phase 1 trial, the first time this product is being tried in people. It looks at safety only, not whether it works, and it is not proven or approved.
Eligibility criteria
Please note this may not be a complete list of eligibility criteria. Inclusion Criteria: * Have decision-making capacity and be able to provide written informed consent. * Are between 18 to 65 years of age * Have genetically confirmed diagnosis of Huntington's Disease * Able to undergo MRI scans, tolerate neurosurgical procedure, blood draws and lumbar puncture. Exclusion Criteria: * Are pregnant * Test positive for human immunodeficiency virus (HIV), hepatitis C or chronic hepatitis B at Screening * Have an implanted deep brain stimulation device.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-04-13