NCT06496425 · RECRUITING

Inspiring Seniors Towards Exercise Promotion to Protect Cognition

This trial tests whether adding personalized, beat-accented music to a six-month exercise program helps older adults with memory worries stay active. Everyone does strength and aerobic exercise. Half also use music. Researchers track activity habits, mood, physical and thinking function, and quality of life. Phase is not applicable, since this is a behavioral study, not a drug trial.

You may qualify if

  • Adults at least 65 years old.
  • Ambulatory/capable of walking without pain or the use of assisted walking devices.
  • Able to speak and read English.
  • Healthy enough to exercise at moderate intensity with or without medical clearance by a primary care physician.
  • Living in the community for the duration of the study.
  • Having a reliable means of transportation.
  • Having a safe place at home or a residential area (at least 6 feet by 6 feet of open space) for unsupervised exercise training.
  • Being low-active (\< 60 min/week of moderate-intensity aerobic exercise and no strength training for the last 3 months).
  • Having SCC, defined by the Cognitive Change Index (CCI) ≥ 15.

You're excluded if

  • Concurrent diagnosis of neurological disorder (e.g., dementia, Parkinson's disease, multiple sclerosis, stroke, etc.).
  • Known exercise contraindications (uncontrolled hypertension, joint problems, diabetes, metabolic conditions etc.).
  • Current cancer treatment.
  • Stroke or neural impairment in the past 6 months.
  • Hip/knee/spinal fracture or surgery in the past 6 months.
  • Unable or unwilling to attend intervention classes.
  • Currently participating in any other physical activity or fitness-related research study.
  • Use of medication for cognitive impairment.
  • Regularly drink > 14 alcoholic beverages a week or current illicit drug use.
  • Meet the threshold for cognitive impairment.
  • Meet the threshold for clinical depression.
  • Uncorrected hearing or visual impairments.
  • Unable to understand the study procedures.
  • One of the household members is participating in this study.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-04-30

View full record on ClinicalTrials.gov

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