NCT06289569 · RECRUITING
Home Tele Rehabilitation Therapy for Vascular Dementia
This trial tests whether physical rehabilitation delivered via video or remote technology at home is practical and reduces caregiver burden for stroke survivors, some of whom also have vascular dementia. It focuses on upper limb movement and arm function. This is a Phase NA feasibility study, meaning researchers are asking whether the approach is workable and safe enough to study further, not whether it is a proven treatment.
You may qualify if
- Symptomatic ischemic or hemorrhagic stroke verified by computerized axial tomography or magnetic resonance imaging
- at least 6 months post stroke
- At least some active movement in the affected upper extremity (MRS 1 or more in shoulder elbow or wrist)
- Ability to provide informed consent, or LAR able to provide consent
- Expressed willingness to comply with all study procedures and attend all study-related visits for both the patient and at least one caregiver.
- Age ≥ 18.
- Ability to follow one-step commands.
- Community-dwelling with transportation to evaluation sessions.
- Ability to operate the therapy system with minimal assistance, including sufficient corrected vision to perceive objects from a distance of 5 feet.
- Modified Ashworth Scale Score 3 or less in the involved upper extremity
- Passive range of motion within functional ranges at the shoulder, elbow, wrist and hand
You're excluded if
- Patients with history of severe alcohol or drug abuse, psychiatric illnesses like severe depression, poor motivational capacity, or severe language disturbances, particularly of receptive nature or with serious cognitive deficits (defined as unable to follow study instructions even with help from caregiver).
- Patients with bilateral paresis, or weakness or sensory damage due to peripheral causes (e.g. peripheral nerve injury, muscle or orthopedic injury etc.)
- Patients with severe uncontrolled medical problems that would render intensive rehabilitation unfeasible or unsafe (e.g. cardiovascular disease, unstable cardiac arrhythmia, severe rheumatoid arthritis, active joint deformity of arthritic origin, active cancer or renal disease, any kind of end-stage pulmonary or cardiovascular disease, or a deteriorated condition due to age, epilepsy or others).
- Concurrent participation in other experimental upper extremity rehabilitation trials that would interfere with results.
- Non-English-speaking individuals will only be eligible if they can provide the appropriate translator for all the sessions of the study as no funding is available to pay for such services. However, we plan to include them once funding has been secured in the subsequent larger trial.
- Pregnancy
- Prisoners
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-03-02