NCT06706687 · RECRUITING
A Study of the Behavioral Variant of Frontotemporal Dementia and Bipolar Disorder: a Neuroimaging and Epigenetics Integrated Approach
This study looks at blood markers called miRNA, plus brain MRI, spectroscopy and PET scans, in people with behavioral variant frontotemporal dementia, people with bipolar disorder, and healthy volunteers. The goal is to see how gene-activity changes relate to brain structure and function. It is a diagnostic, observational-style study, not a test of a treatment.
You may qualify if
- byFTD group: patients of either sex; 18 years of age or older; diagnosis of behavioral variant Frontotemporal Dementia according to current diagnostic criteria; presence of a signed informed consent.
- BD group: patients of either sex; 18 years of age or older; diagnosis of bipolar disorder according to DSM-V criteria; presence of a signed informed consent.
- HC group: patients of either sex; 18 years of age or older; subjects who have gone through the same diagnostic process as patients under suspicion of a central nervous system and/or psychiatric disorder, resulting in the absence of cognitive deficits and mood disorders; presence of a signed informed consent.
You're excluded if
- Diagnosis of Alzheimer's disease
- Comorbidities interfering with the studied condition (e.g. other neurological diseases or history of substance or alcohol abuse)
- Diseases with an inflammatory component (e.g. autoimmune diseases, tumors)
- Pregnancy
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-11-26