NCT07659964 · RECRUITING
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
This study tests whether walking to a steady metronome beat changes how people with mild Alzheimer's or MCI walk, and how their brains work while walking. Researchers use portable brain and body sensors to measure this. It is not a drug trial, and the phase is listed as not applicable. Results would be early, not proof of benefit.
Eligibility criteria
Inclusion Criteria: General Inclusion (both healthy and AD populations): * Community-dwelling * Capable of walking short community distances (approximately 10-15 minutes at a time) without assistance from another person or a device (such as a cane). * Able to communicate with researchers * Age 50-90 (inclusive) Population-specific Inclusion criteria: * Healthy - * No diagnosis of AD * AD population- CERAD score of \<1.5 SD from age + education adjusted norms on delayed recall domain or one or more other cognitive domains (i.e. language, attention). MoCA score between 20-30 MMSE score between 25-30 Exclusion Criteria: * Presence of significant hearing impairment * Current orthopedic, neurologic or other medical condition that limits the ability to walk. The MOCA, MMSE and CERAD tests will be completed in-person after the participant consents into the study. If the participant is determined to be ineligible based on their performance on these tests (compared to inclusion requirements listed above), they will be informed that they are not eligible for this study and the study visit will be cancelled. They will then be withdrawn from the study; their clinical tests and study documentation will be maintained for the purposes of completeness, but will not be used for any study analyses.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-08-13