NCT03503331 · Phase 2 · RECRUITING
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy
This study uses PiB-PET brain scans and MRI to measure how much amyloid, a sticky protein linked to Alzheimer's, has built up in the brain and where. Researchers also look at how race, vascular risk factors like blood pressure, and thinking ability relate to amyloid levels. It is an imaging study, not a treatment test.
Eligibility criteria
Inclusion Criteria: - 1. Enrollment in the UAB-ADC study under a separate IRB-approved research protocol (IRB-300000169). 2. Negative urine or serum B-hCG test within 2 days of [C-11]PiB administration in women of child bearing potential. Women who are post-menopausal with at least 1 year since last menses or documented surgical sterilization will not require pregnancy testing. Exclusion Criteria: 1. Meets any exclusion criteria for the UAB-ADC study (IRB-300000169). 2. Inability or contraindication for undergoing MRI and/or PET imaging 3. Inability to participate in the imaging studies due to severity of dementia
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-08-12