Trials in Alabama.

This trial tested bapineuzumab, an infused antibody designed to bind and clear beta amyloid from the brain, against a placebo. It measured whether it helped…

This trial tested whether bapineuzumab, an antibody given by infusion that helps clear beta amyloid from the brain, could affect thinking and daily function in…

This Phase 2 trial tested lecanemab, an anti-amyloid antibody given by infusion, in people with early Alzheimer's disease — either mild cognitive impairment or…

This Phase 3 trial is testing lecanemab, an anti-amyloid antibody drug, in people who are cognitively normal but have early amyloid buildup in their brains —…

This trial tested bapineuzumab, an antibody drug given by infusion, against a placebo in people with mild to moderate Alzheimer's. It looked at how well the…

This trial tested bapineuzumab, an antibody drug given by infusion, against a placebo in people with mild to moderate Alzheimer's. Researchers measured safety…

This trial looked at the long-term safety and tolerability of bapineuzumab, an antibody drug given by infusion, in people with Alzheimer's who had finished an…

This trial tests whether a more precise form of whole-brain radiation can spare the hippocampus, the brain's memory center, in people whose cancer has spread…

Enroll-HD is an observational study, meaning no drug or treatment is given. It follows people with Huntington's disease, and their relatives and controls,…

This trial tests several investigational drugs, including gantenerumab, solanezumab, E2814 and lecanemab, against placebo. It asks whether they slow cognitive…

This Phase 3 trial tested solanezumab, an antibody drug given by IV infusion, in cognitively normal older adults who already had amyloid buildup in their…

This Phase 3 trial tested whether LCZ696 (sacubitril/valsartan, sold as Entresto) protects cognitive function better than valsartan alone in people with a…

This study uses PiB-PET brain scans and MRI to measure how much amyloid, a sticky protein linked to Alzheimer's, has built up in the brain and where.…

This study uses a brain scan, a PET scan with a tracer called AV-1451, to look at where tau builds up in the brain. Tau is a protein tied to Alzheimer's.…

This trial tests AMT-130, a gene therapy delivered by brain surgery into a deep brain region called the striatum, in adults with early Huntington's disease. It…

PREVENTABLE is a large Phase 4 trial testing whether atorvastatin 40 mg — a common cholesterol-lowering statin — can reduce the combined risk of death,…

This is a large North American research registry and natural history study tracking people with frontotemporal lobar degeneration (FTLD) and related conditions…

This trial is testing a staff training program called MAP-VA at eight VA long-term care facilities. The program teaches employees Montessori-based,…

This trial tests donanemab, an anti-amyloid antibody given by infusion, against a placebo in people with no memory or thinking problems but signs of amyloid in…

This trial is testing a behavioral coaching program called CuRB-IT, designed to help family caregivers manage moments when a person with dementia resists or…

This trial tests two school-based behavioral programs — ReACT, a school-wide anti-racism intervention, and Coping Power+, a targeted program for at-risk 7th…

This trial tests two investigational drugs, E2814 and lecanemab, in people who carry a gene mutation that causes early-onset Alzheimer's. It measures changes…

This Phase 3 trial is testing KarXT, an oral drug, to see whether it prevents the return of psychosis symptoms — hallucinations and delusions — in people who…

This trial is testing CT1812, an experimental drug, in people with early Alzheimer's disease — either mild cognitive impairment or mild dementia confirmed by…

This Phase 2 trial is testing remternetug, an anti-amyloid antibody given by injection, in people who carry a rare genetic mutation (in APP, PSEN1, or PSEN2)…

This trial is testing tominersen, a drug injected into the spinal fluid, against a placebo in people with prodromal or early Huntington's Disease. The goal is…

This study records brain activity in epilepsy patients who are already having brain electrodes implanted for seizure monitoring. Researchers want to understand…

This trial is testing whether KarXT, a drug targeting certain brain receptors, is safe to take for up to a year in people who already have Alzheimer's-related…

This pilot study is testing whether EEG-guided alpha neurofeedback training and visual attention exercises can improve processing speed and daily functioning…

This trial gives lecanemab, an anti-amyloid antibody, to people who carry a gene mutation that causes inherited Alzheimer's, and who already took part in an…

This observational study tracks the mental health and well-being of Hispanic and Latino caregivers who look after a family member with memory problems or…

This study follows people with early symptomatic Alzheimer's in the US to compare those who take donanemab (an anti-amyloid antibody drug) plus usual care with…

This trial tests remternetug, an anti-amyloid antibody drug, in people who carry a gene mutation that causes early-onset Alzheimer's and who still have normal…

This trial tests remternetug, an anti-amyloid antibody drug, against a placebo. It measures how long it takes for memory, thinking, or daily-function problems…

This study is mapping specific genetic markers called SNPs in people who carry the Huntington's disease gene mutation. Participants give a blood sample and…

This Phase 2 trial is comparing two medications — pramipexole (a dopamine-targeting drug used in Parkinson's and restless legs) and escitalopram (a common…

This study tests whether an app-based mindfulness program, called the Healthy Minds Program, can help protect the mental health of teachers in their final year…

This trial tests BMS-986368, an experimental drug that works on the body's endocannabinoid system, to see whether it reduces agitation in people who already…

This trial is testing a multimodal lifestyle intervention — combining multiple lifestyle changes at once — to see whether it can reduce dementia risk factors…

This trial is testing trontinemab, an anti-amyloid antibody drug, against a placebo in people with early Alzheimer's disease — specifically those at the MCI or…

This is not a treatment trial. It is a pre-screening study run by Roche to figure out who might qualify for their future Alzheimer's disease trials.…

ASPREE-XT is following older adults who were previously in the ASPREE aspirin trial to see what happens after they stopped taking aspirin. Researchers are…

This study compares two short, phone-delivered programs over four weeks: one teaches behavioral strategies for insomnia, the other teaches mindfulness.…

This trial is testing votoplam, an oral drug designed to slow the progression of early-stage Huntington's disease. Researchers are comparing it against a…

This trial is testing whether a ketone supplement (a drink that gives the brain an alternative fuel source) can temporarily improve thinking speed and brain…

This trial tests whether a drug called pridopidine can slow the worsening of Huntington's disease over one year, compared with a placebo. It looks at movement,…