NCT07865260 · NOT YET RECRUITING
PhiCube for Bilateral Upper Limb Neuromotor and Cognitive Rehabilitation in Adults
This trial tests PhiCube, a small, portable robotic device that guides both arms through exercises. Researchers are checking how easy it is to use and whether it is safe, then looking at arm movement and thinking skills. Everyone also gets standard rehab. It is a pilot study of 80 adults, an early, small test, not proof it works.
Eligibility criteria
Inclusion Criteria: Group 1 (neuromotor impairment): * Adults aged 18 to 85 years * Diagnosis of a neuromotor disorder affecting the upper limbs, such as stroke, amyotrophic lateral sclerosis, Parkinson's disease or spinal cord injury * Able to provide informed consent Group 2 (cognitive impairment): * Adults aged 18 to 85 years * Diagnosis of mild cognitive impairment defined by a MoCA score between 18 and 25 * Able to provide informed consent Exclusion Criteria (both groups): * Severe cognitive or behavioural impairment (MoCA below 18) * Severe upper limb motor impairment, defined as an MRC score below 3 in deltoid, biceps and triceps * Impairment of upper limb range of motion that is non-modifiable or painful * Recent upper limb joint injury or joint prosthesis, risk of shoulder dislocation (for example shoulder subluxation), severe osteoporosis, or severe spastic hypertonia of elbow and wrist flexors according to medical judgement * Contraindications to robotic therapy, that is unstable health conditions that could make the use of the device dangerous or inappropriate, such as severe cardiovascular disease, severe respiratory disease or other unstable medical conditions * Participation in another clinical trial within the 30 days before enrolment
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-10-08