NCT06935812 · RECRUITING
Comparison of the Effects of Bimanual, Finger and VR Exercises in PwMCI
This trial compares three types of physical exercise in people with mild cognitive impairment: coordinated two-handed movements, finger exercises, and virtual reality activities. Researchers want to see which approach does the most for thinking and memory skills. This is a Phase NA study, meaning it is a direct comparison between approaches rather than a staged drug development trial. Details on sample size and outcome measures are limited in the source.
You may qualify if
- Participants who are between 50-75 years of age
- Individuals diagnosed with MCI by a geriatrician according to DSM-5 criteria,
- Who has the Montreal Cognitive Assessment score between 13-26,
- Who has the Quick Mild Cognitive Impairment screen score between 48-67,
- Who has Instrumental Activities of Daily Living Scale score ≥6/8,
- Who says yes to "Do you have a memory problem?" question,
- Who can walk independently without using any walking aids
You're excluded if
- Participants who have any musculoskeletal disorders that may cause balance and gait disorders,
- Who have central or peripheral neurological diseases (eg. stroke, Parkinson's disease or polyneuropathies),
- Who are using psychiatric drugs that may affect psychiatric disease and/or cognitive performance (Using nonsteroidal anti-inflammatory drugs more than three times a week, which may affect cognitive functions, using gingko biloba and antioxidant supplements (for example, coenzyme Q10 and alpha-lipoic acid)),
- Who has daltonism and
- Who attends any exercise program last 6 months will not be included in this study.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-05-19