NCT07401849 · NOT YET RECRUITING
Blood Biomarkers for Early and Accurate Diagnosis of Alzheimer's Disease in Primary Care
This study tests whether a specific blood test, used in a regular primary care office, can help spot Alzheimer's disease early in people 55 and older who have memory or thinking concerns. It is a diagnostic study, not a drug trial. No phase was listed, and no treatment is being given.
You may qualify if
- Age 55 years and above
- Presence of self-reported symptoms indicative of cognitive decline or concerns family members/partners indicative of cognitive decline
- Capacity to consent
- Be fluent in and able to read and write in English and have adequate hearing and visual acuity to complete the required psychometric tests.
You're excluded if
- Insufficient vision and hearing
- Prior diagnosis of ADRD. Prior diagnosis of Alzheimer's disease or related dementia (with or without evidence of pathology), through clinical diagnosis and/or as documented in their medical record
- Pre-existing diagnosis of dementia
- Incidental findings of brain pathologies on brain MRI, such as cancerous space occupying lesions and clinically significant vascular malformations and recent (within 12 months) macro-infarcts, that are, also exclusionary
- Contraindication for Lumbar Puncture
- Involvement in interventional research study within 3 months prior to screening
- For any other reason, in the opinion of the Investigator, participating in the study is not in the best interest of the patient.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-02-11