NCT03263247 · ACTIVE NOT RECRUITING
Cognitive Training in Patients With MCI Using fMRI
This trial is testing whether two types of cognitive training — a visual memory technique and an alphabet-search exercise — improve brain function in people with amnestic mild cognitive impairment (MCI), compared to a psychoeducation control group. Brain changes are measured with fMRI. It is a Phase NA study, meaning it is a behavioral research study rather than a drug trial moving through standard approval phases. Details beyond the summary are limited.
You may qualify if
- Portuguese as native and preferred language; A minimum of 4 years of education; MRI-compatible; Right-handed individuals; Normal corrected vision and hearing; Estimated intelligence average or above (≥ 80 IQ); Amnestic Mild Cognitive Impairment identified by a doctor and neuropsychological tests; Able to give informed consent.
You're excluded if
- History of neurological disorder; History of serious systemic disease; History of severe mental illness; Current untreated alcohol or substance abuse; Medical conditions that compromise in any way the central nervous system; Presence of visual impairment and / or hearing to preclude cognitive testing; Presence of contraindications to MRI exam; Findings in structural MRI that can interfere with the results of the study
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-07-09