NCT07766993 · NOT YET RECRUITING
Developing and Testing an AI-Based Cognitive Intervention Program
This trial is testing whether an AI-guided lifestyle program — covering diet, exercise, mental activity, sleep, social connection, and stress — can help protect memory and thinking skills over one year. It also tracks a blood marker called p-tau217, which is linked to Alzheimer's disease. This is a Phase NA study, meaning it is evaluating a behavioral program rather than a drug — it is not yet proven or approved.
You may qualify if
- Chinese community-dwelling residents aged ≥ 40 years;
- Cognitive function adequate to cooperate with testing and interventions;
- No history of major neurological or psychiatric disorders;
- Not on long-term use of medications known to affect cognitive function significantly ;
- Possess the basic access and ability to use smartphones or the internet to receive online interventions;
- Good compliance, with the expected ability to adhere to and complete a 1-year follow-up.
You're excluded if
- Age \< 40 years;
- Cognitive function inadequate to cooperate with testing and interventions;
- History of major neurological disorders (e.g., stroke, Parkinson's disease, brain tumors, epilepsy) or severe psychiatric disorders (e.g., schizophrenia, severe depressive episodes);
- Currently taking medications known to significantly affect cognitive function (e.g., anticholinergic drugs, certain psychotropic medications);
- Presence of severe systemic or physical illnesses (e.g., advanced malignancy, severe heart, lung, liver, or kidney failure);
- Lack of access to smartphones or the internet, rendering the participant unable to receive online interventions;
- Any other conditions deemed by the investigator as inappropriate for participation in this study.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-08-18