Effectiveness of Non-pharmacological Interventions for Dementia Prevention in Elderly Patients With Mild Cognitive Impairment

Eligibility criteria

Inclusion Criteria:
* Subjects diagnosed with mild cognitive impairment:
  * Cognitive complaints from the subject or a family member.
  * Report a decline in cognitive function compared to the subject's previous ability over the past year OR
  * Evidence from clinical assessment, specifically here is MMSE screening with results of 24-29 points.
  * Subjects did not suffer major impacts from cognitive complaints on daily life.
  * No prior diagnosis of dementia.
* Ensure transportation from living location to hospital.
* Have at least one relative or caregiver who can supervise the subject's daily activities.
* Stable chronic underlying conditions (diabetes, hypertension).
* Consent to participate in the study.
Exclusion Criteria:
* Don't know Vietnamese writing.
* Audio-visual ability does not meet the requirements of assessment tests and prevention programs.
* Systemic diseases are contraindications/ restriction to participation in programs and/or cause secondary cognitive impairment (traumatic brain injury, stroke, brain tumor, parkinsonism, epilepsy, acute coronary artery disease, acute myocardial infarction, bone fractures...).
* The assessment score on the Geriatric Depression Scale (GDS-15) is ≥ 5 points.
* Diagnosed with other mental disorders that may limit the ability to understand, communicate and work in groups (schizophrenia, mania, bipolar disorder, dissociative disorder, generalized anxiety disorder).
* Currently participating in another research program on dementia prevention or a research program on medication to prevent dementia within the last 3 months.
* Taking medications that may affect cognitive function, such as benzodiazepines, hypnotics, and antipsychotics.
* Alcohol abuse: drinking alcohol daily or consuming more than 14 units of alcohol per week (equivalent to 10 grams of ethanol, as defined by the Ministry of Health); diagnosed with alcohol dependence or currently being treated for mental illness due to alcohol dependence.
* Do not agree to participate in the study.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2024-09-19