NCT06372535 · UNKNOWN
Effects of Tai Chi Chuan With Different Doses on Cognitive Function in Elderly Patients With Mild Cognitive Impairment
Sponsor: Lidian Chen
This trial is testing whether Tai Chi Chuan helps cognitive function in older adults with mild cognitive impairment, and whether the amount of Tai Chi practiced makes a difference. Nine different exercise doses are being compared. It is a Phase NA trial, meaning it is a practical behavioral study rather than a drug trial moving through standard approval phases. It is designed to find the most effective exercise volume, not to approve a product.
You may qualify if
- Presence of mild cognitive impairment, not demented;
- Age ≥ 60 years old;
- Informed consent and voluntary participation.
You're excluded if
- Geriatric Depression Scale score ≥ 9 points
- Cognitive impairment caused by other reasons, taking drugs, poisoning, etc;
- Suffer from severe musculoskeletal system diseases and other contraindications to exercise and are not suitable for Tai Chi training, such as those who suffer from stroke, Parkinson's disease, and have a history of lower limb arthritis, hip and knee joint replacement, etc;
- Patients with severe heart, liver, kidney failure, malignant tumors, and other major diseases;
- Individuals with visual/auditory impairments, writing/reading impairments, illiteracy, etc. that affect training and evaluation;
- Individuals with uncontrolled hypertension (systolic blood pressure greater than 160mmHg or diastolic blood pressure greater than 100mmHg after medication);
- Participating in other experiments that influence this study;
- Engaged in regular exercise in the last three months (at least 3 times a week, at least 20 minutes of regular exercise each time.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-04-18