NCT06832761 · RECRUITING

Lifestyle Intervention in the Memory Clinics of General and Academic Hospitals Trial

This trial tests whether a personalized lifestyle program can help protect thinking and memory in older adults with subjective cognitive decline or mild cognitive impairment. It includes coaching, a voucher program, and online self-management over 12 months, compared with general health advice. The trial is labeled Phase NA because it tests behavior, not a drug.

You may qualify if

  • ≥50 years of age at pre-screening;
  • Having a diagnosis of SCD or MCI;
  • Presence of ≥ 2 modifiable risk factors for dementia.

You're excluded if

  • Having a diagnosis of dementia;
  • Insufficient understanding of the Dutch language;
  • Conditions affecting safe and continuous engagement in the intervention (e.g. under treatment for current malignant diseases, major psychiatric disorders (e.g. major depression, psychosis, bipolar disorder), other conditions preventing co-operation as judged by the local study nurse or consulted physician at the local study site;
  • Participation in any other research intervention trial at time of pre-screening and throughout the study period.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-10-15

View full record on ClinicalTrials.gov

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