NCT07722169 · NOT YET RECRUITING
Telerehabilitation in Alzheimer's Disease
This study tests whether brain-training exercises done at home on a tablet with virtual reality-based games help people with mild-to-moderate Alzheimer's, and whether a neuropsychologist supervising online makes a difference. It also compares costs and burden of home versus hospital training. It is not a drug trial, and no phase applies.
Eligibility criteria
Inclusion criteria for patients with Alzheimer's disease (AD): * Age between 50 and 90 years. * Diagnosis of Alzheimer's disease according to established diagnostic criteria. * Mini-Mental State Examination (MMSE) score between 18 and 24. * Stable pharmacological treatment for at least 3 months before enrolment. * Ability and willingness to provide written informed consent. Inclusion criteria for caregivers: * Age ≥18 years. * Availability to assist the patient throughout the study. * Ability and willingness to provide written informed consent. Exclusion criteria for patients with Alzheimer's disease (AD): * Refusal or inability to provide written informed consent. * History of psychiatric disorders. * Significant cerebrovascular disease. * Severe visual or hearing impairment that could interfere with study procedures. * Psychosis. * Major depressive disorder. * Alcohol or substance abuse. * Use of psychotropic medications that may interfere with neuropsychological assessment or study treatment. * Concurrent participation in another interventional pharmacological clinical trial. * Any contraindication to undergoing EEG recording. Exclusion criteria for caregivers: * Refusal or inability to provide written informed consent. * History of psychiatric disorders. * Major depressive disorder. * Alcohol or substance abuse. * Use of psychotropic medications that may interfere with neuropsychological assessment.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-08-03