NCT06492109 · RECRUITING
The Peripheral Blood Multi-Omics Study on Sleep Loss
This study is looking at what happens in the blood when people lose sleep. Researchers will use detailed molecular analysis (multi-omics) to measure changes in genes and metabolism after sleep deprivation across different age groups and cognitive levels. The goal is to better understand the biological link between poor sleep, aging, and Alzheimer's disease. This is a Phase NA observational and behavioral study — it is gathering information, not testing a treatment.
You may qualify if
- Signed informed consent form；
- Meet the inclusion criteria for each arms.
You're excluded if
- Failure to provide informed consent;
- Inability to follow study procedures due to issues such as language barriers or cognitive impairment;
- Regular use of medications that may alter the relationship between sleep and outcome variables (e.g., opioid medications, benzodiazepines, and Z drugs [non-benzodiazepine hypnotics]);
- History of alcohol abuse, substance abuse, consciousness disorders, cerebrovascular disease, head injury, epilepsy, encephalitis, or other neurological disorders;
- Diagnosis of schizophrenia, severe depression, anxiety disorders, or other severe psychiatric conditions;
- Presence of severe arrhythmias, myocardial infarction within the last 6 months, severe pulmonary dysfunction, renal or hepatic insufficiency, severe anemia, severe gastrointestinal diseases, tumors, or other severe medical conditions.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-07-31