NCT06878430 · NOT YET RECRUITING

Reducing Risk of Stroke and DementIa In patientS With COVert cERebrovascular Disease

This is a pilot study, a small first step, for adults 65 and older whose past brain scans showed silent signs of blood vessel damage but who have never had a stroke or dementia diagnosis. It tests how to reach and follow these people, tracking thinking and daily function scores. No treatment is being tested. Phase not specified.

Eligibility criteria

Inclusion Criteria:
* People who, at the time the letter is prepared or are identified by a clinician
  * Age ≥ 65 years
  * Have no known history of:
    * Stroke or TIA
    * Dementia
    * Parkinson's disease
    * Multiple sclerosis
    * Metastatic cancer (or non-meningioma brain tumour).
  * A CT or MRI scan report ≤5 years before study start date with of one or more of:
    * Cerebral small vessel disease
    * Deep old ischaemic stroke
    * Cortical old ischaemic stroke
Exclusion Criteria:
* Text of brain scan report unreadable
* Do not consent to take part in study procedures
* Unable to consent
* Unable to communicate by email, letter or telephone through language, speech disability or lack of address
* Unlikely to survive one year past enrolment in judgement of the study investigator

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-09-09

View full record on ClinicalTrials.gov

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