NCT06542458 · ENROLLING BY INVITATION
Under-Represented Communities Diagnosed With SCD or MCI Through Tele-Cog
Sponsor: Ohio State University
This observational study is following older adults from underrepresented and under-resourced communities who have already been diagnosed with subjective cognitive decline or mild cognitive impairment through a telehealth clinic. Researchers are collecting assessments, brain imaging, and biofluid samples over time to better understand how these conditions progress. There is no experimental treatment — participants are being studied, not treated. The phase is unspecified, consistent with an observational registry study.
You may qualify if
- Adults ages 50 years and older
- Diagnosed with subjective cognitive concerns (SCD) or objective cognitive decline with mostly intact functioning (MCI diagnosis) as part of clinical work up
- Fluent in English
- Able to provide voluntary informed consent
- Willing and able to undergo all study procedures
- Able to delegate, if possible, a study partner. The study partner must be ≥18 years of age and must know the patient well enough to contribute information regarding the patient's daily activities and cognition.
- Must also consent to the Neuroscience Research Institute Brain Bank and Biorepository (NRI-BBB) Banking Protocol (OSU protocol 2020H0512).
You're excluded if
- Diagnosis of dementia at baseline.
- Inability to give informed consent.
- High risk of adverse emotional or behavioral reaction based on investigator's clinical evaluation (e.g., evidence of serious personality disorder, antisocial behavior, serious current stressors, lack of meaningful social support).
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-10-16