NCT07143734 · Phase 2 · RECRUITING
Transcranial Pulse Stimulation for Alzheimer's Disease
This trial tests whether transcranial pulse stimulation, a device that sends gentle, focused pulses through the skull, can help people with early-stage Alzheimer's. It compares real stimulation with a sham (fake) version. The source doesn't list the outcome measures. It is a Phase 2 trial: testing whether it works and is safe, not yet proven or approved.
Eligibility criteria
Inclusion Criteria: * Adults who have been clinically diagnosed with Alzheimer's Disease in the early stage 2-6a according to the Functional Assessment Staging Test (In Appendix A) * The mental capacity to give informed consent for research is made by an experienced geriatrician based on Appendix A. * Aged 60-90 years old. * Able to make informed consent under assistance, which is witnessed and signed by a family caregiver. Exclusion Criteria: * Cannot understand Chinese. * Mentally incapacitated, unable to provide informed consent * Inability to remain still for 30 minutes * Lack of available family caregiver to answer questionnaires * Alcohol or substance dependence * Major neurological conditions, including: * Brain tumor * Brain aneurysm * Presence of any metal implants in the brain * Hemophilia or other blood clotting disorders * History of thrombosis
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-09-16