NCT07839650 · RECRUITING
Transcranial Alternating Current Stimulation (tACS) Combined With Cognitive Training in Alzheimer's Disease
This trial tests whether a gentle electrical brain stimulation device, worn on the head, combined with computer-based memory training can improve thinking and memory in people with mild Alzheimer's disease. Half get real stimulation, half get a fake version. It is a small study of 30 people with no phase label, so it is early and unproven.
Eligibility criteria
Inclusion Criteria: Patients: * Male or female participants aged ≥18 years at the time of signing the informed consent form; * Clinical diagnosis of mild Alzheimer's disease (AD) according to current clinical criteria; * Availability of a caregiver who can assist the participant and who has successfully completed the required training for the use of the device at home. Caregivers: * Male or female caregivers aged ≥18 years; * Compliance with participation in the in-hospital training; * Mini-Mental State Examination (MMSE) score >27/30. Exclusion Criteria: * Age below that specified in the inclusion criteria; * Inability to understand; * Contraindications to tACS and TMS (e.g., presence of a cardiac pacemaker or metallic implants incompatible with electrical or magnetic fields, history of epilepsy, or current pregnancy, as assessed using the safety questionnaire).
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-09-24