NCT06473714 · RECRUITING

Effects of Transcranial Direct Current Stimulation (tDCS) on Inhibition and Brain Function in Primary Progressive Aphasia

This trial tests whether mild electrical stimulation to the scalp, called tDCS, changes brain activity and thinking skills like inhibition in people with primary progressive aphasia, a language-focused form of dementia. Some get real stimulation, some get a sham version. It is not a phase-labeled drug trial, so it is early research, not proven.

You may qualify if

  • Be a male or female over the age of 18 with a primary progressive aphasia diagnosis
  • Available for treatment and testing sessions
  • able to read and speak French
  • Be right-handed

You're excluded if

  • Presence of neurodevelopmental disorders or non-degenerative neurological disorders
  • Post-stroke aphasia
  • Language or cognitive disorders too severe to allow task performance or communication
  • Pre-existing psychiatric disorders; severe depression, schizophrenia
  • People with pacemakers or metal implants, epilepsy
  • Presence of a medical condition that represents a contraindication to tDCS
  • Active use of psychotropic drugs
  • Treatment with tDCS or TMS in the last 3 months
  • Additional language therapy
  • Pregnancy or breast-feeding

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2024-11-05

View full record on ClinicalTrials.gov

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