NCT05573490 · RECRUITING
Lifestyle Interventions for the Treatment of Early Onset Alzheimer's Disease Study
This study tests whether computer-based brain training plus Tai Chi and Qi Gong can help people with early-onset Alzheimer's keep up their thinking, daily functioning, and mood, compared with brain games and stretching. It has no phase label. It is an early look to gather preliminary data, not proof that anything works.
Eligibility criteria
Inclusion Criteria: * Enrolled in the Longitudinal Early-Onset AD Study (LEADS) parent study, and being classified via LEADS consensus criteria as having amyloid-positive Early Onset Alzheimer's Disease * Aged 40-64 years at the time of enrollment into LEADS * Fluent in English * In good general health and absent another neurological disorder * Have a knowledgeable informant. * Have had a Clinical Dementia Rating scale of 0.5 to 1.0 at the time of enrollment into LEADS * Have sufficient vision, hearing, comprehension, and manual dexterity to participate in the testing and training program Exclusion Criteria: • Have access to the internet (e.g., home, family, public library, etc.) for less than 4 hours per week
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-05-06