NCT01334749 · ACTIVE NOT RECRUITING
Observational Study on Determinants of Dementia After Stroke
This is an observational study, meaning no drug or treatment is given. Researchers follow people in Germany who have just had a stroke and had no dementia before. Over 10 years, they use brain scans and blood tests to learn what predicts who develops dementia afterward. It is not a test of any treatment.
Eligibility criteria
Inclusion Criteria: * Age ≥ 18 years * Language: German * Acute stroke that occurred within the last 5 days as defined by: acute focal neurological deficit in combination with one of the following: * An acute ischemic infarct as documented by either a DWI positive lesion on MR imaging or a new lesion on a delayed CT scan * An intracerebral hemorrhage as documented on CT or MRI * An informant of the patient is available * Written informed consent by patient prior to study participation * Willingness to participate in follow-up Exclusion Criteria: * IQCODE > 64 or diagnosis of dementia * Patients transferred from an outside stroke unit (to avoid possible selection bias) * Patients presenting a stroke going back more than 120 hours * Patients presenting one of the following diseases: cerebral venous thrombosis, traumatic cerebral haemorrhage, intracerebral haemorrhage because of a known or image-guided assumed vascular malformation, pure meningeal or intraventricular haemorrhage * Patients presenting a malignant disease with life expectancy \< 3years * Contraindication for MRI * Participation in an intervention/AMG-study at baseline
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2024-03-20