NCT07166224 · RECRUITING
The Effect of Regular Home Use of Dual-light Antibacterial Photodynamic Therapy (aPDT) or the Use of a Powered Toothbrush in Older Individuals With Periodontitis and Mild Cognitive Impairment.
This trial compares three home gum-care routines in older adults with gum disease and mild cognitive impairment. Two groups try a light-based device (Lumoral) with a manual brush, or a powered toothbrush. A third uses a basic manual brush. Researchers track plaque, gum bleeding, pocket depth, bad breath, and quality of life. It is not a drug trial, and no phase applies.
You may qualify if
- Adults aged ≥60 years
- ≥15 teeth
- Diagnosed periodontitis stage I-III
- MMSE score between 22-28
- Able to provide informed consent
You're excluded if
- Antibiotic use (within 3 months)
- Lumoral use within 3 months
- Bisphosphonate medication
- Immunosuppressive drugs or radiation therapy
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-10-01