NCT02299037 · UNKNOWN
Predicting the Risk of Post-operative Delirium: Use of Neuropsychology, Serum and CSF Biomarkers and Genetics to Predict Risk of Post-operative Delirium
This is an observational study, not a drug test. Researchers are checking whether memory and thinking tests, APOE4 status, and blood and spinal fluid markers before hip or knee surgery can predict who gets post-operative delirium, a sudden spell of confusion. Phase is unspecified. A follow-up about 8 years later looks at later thinking changes.
You may qualify if
- living at home
- undergoing primary, elective hip or knee arthroplasty
- spinal anaesthetic with intrathecal diamorphine anticipated
You're excluded if
- neurological, hearing or visual disability affecting ability to participate in study
- known neurodegenerative condition eg dementia, Parkinson's disease, multiple sclerosis
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2023-12-26