NCT07634055 · RECRUITING
Assessment of Motor Reserve in the Preclinical Stages of Dementia
This observational study uses a sensor-based hand device to measure how people move, comparing healthy adults with people who have mild cognitive impairment (MCI). Researchers want to understand whether movement ability helps the brain cope with early memory and thinking changes. Nobody receives a treatment. Phase isn't specified, since this is a measurement study, not a drug test.
Eligibility criteria
Inclusion Criteria: * Patients with Mild Cognitive Impairment (MCI) group * Diagnosis of MCI according to the international criteria of the National Institute on Aging-Alzheimer's Association (NIA-AA) (Albert et al., 2011; McKhann et al., 2011). * Age between 40 and 85 years. * Native Italian speaker or sufficient Italian language proficiency to understand the tests. * Signed informed consent provided by the participant or by a legal representative. * Healthy subjects group * Normal performance on the neuropsychological screening assessment. Age between 40 and 85 years. * Native Italian speaker or sufficient Italian language proficiency to understand the tests. * Signed informed consent. Exclusion Criteria: * Patients with Mild Cognitive Impairment (MCI) group -History of psychiatric or neurological disorders not attributable to MCI. Use of psychotropic medications. * Healthy subjects group * History of psychiatric or neurological disorders. * Use of psychotropic medications. * Disabling medical comorbidities or medical conditions interfering with motor function.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-06-08