NCT07775625 · RECRUITING
Central Auditory Processing Modulation Underlying Anxiety Reduction Using Clinically Designed Improvisatory Music
This pilot study tests whether a specialized form of live music — slow, soft, and structured to promote calm — can reduce anxiety in people already diagnosed with Alzheimer's disease. It also measures whether that relief extends to their caregivers. Participants are randomly assigned to either the music sessions or calming storytelling over four weeks. This is a Phase NA feasibility study, meaning researchers are checking whether the approach is practical and shows early promise, not proving it works.
You may qualify if
- Clinical diagnosis of Alzheimer's Disease
- Positive Alzheimer's disease biomarkers (blood test, amyloid PET scan or CSF)
- Mini-mental State Exam (MMSE) >=15
- Rating for Anxiety in Dementia (RAID) score > 8
You're excluded if
- Significant hearing impairments
- Major comorbidities Beck Depression Inventory (BDI) scores above > 10'
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-08-20