NCT05943834 · RECRUITING

Early Detection of Alzheimer's Disease and Affective Disorders by Automated Voice and Speech Analysis (PLATA)

Sponsor: Centre Hospitalier Universitaire de Nice

PLATA is testing whether an algorithm can detect early signs of Alzheimer's disease by analyzing how people speak during a phone-based cognitive task. Researchers will compare speech patterns against established biological markers like CSF proteins and PET scans. This is a diagnostic research study, not a clinical drug trial — the goal is to see if voice analysis could one day replace invasive testing like lumbar punctures. Details on phase are limited.

You may qualify if

  • Age ≥ 50 years
  • Diagnosis relevant biomarker and neuropsychological data already available
  • Cognitively healthy to very mild dementia (CDR score max. 0.5)
  • Sufficient knowledge of the study language to understand study information, non opposition form,and questionnaires
  • Expression of non opposition

You're excluded if

  • Hearing problems
  • Patient protected by law, under guardianship or curator ship, or not able to participate in a clinical study according to the article L.1121-16 of the French Public Health Code

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-03-19

View full record on ClinicalTrials.gov

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