NCT06853405 · RECRUITING
Nutrition-based Interventions to Prevent Cognitive Decline
This study tests a combined lifestyle program for adults at higher risk of dementia. It includes group sessions on nutrition and physical activity, cognitive training at home, and one-on-one nutrition consultations. Researchers want to know if the program is practical and whether it helps thinking skills. It is not a drug trial, so there is no phase. It is early-stage research.
You may qualify if
- Aged from 55 to 85 years old;
- At least 4 years in the regular school system;
- Higher individual risk for dementia defined as a score ≥6 points on the Cardiovascular Risk Factors, Aging and Dementia Dementia Risk Score (CAIDE).
You're excluded if
- Montreal Cognitive Assessment (MoCA) score lower than the validated cutoff points defined as 2 standard deviations below the normative reference value for the corresponding age and education in the Portuguese population;
- Having a medical condition limiting the participation in the intervention (e.g., blindness, amputation…);
- Lack of autonomy in daily activities;
- Diagnosis of dementia or major incapacity.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-12-05