NCT07265323 · RECRUITING
Effect of Physiologic Insulin Administration on Insulin Sensitivity and Cognition
This trial tests whether short weekly insulin sessions, each lasting up to 2 hours for 6 months, change how the body uses glucose and affect memory and thinking in adults with Alzheimer's. Researchers will use cognitive tests and brain glucose scans. It is an early-stage study with no assigned phase, focused on safety and feasibility, not proven.
You may qualify if
- Mini Mental State Examination (MMSE) score \< 25
You're excluded if
- On daily medication for the specific treatment of anxiety including benzodiazepines.
- An infant, child, or teenager
- A pregnant woman
- A prisoner
- Having any condition that impedes testing of the study hypothesis or are otherwise deemed to be unsuitable (determined by the investigative team).
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-12-04