NCT07673770 · RECRUITING
Brain Wave Informed Non-invasive Brain Stimulation: Improving Neural Networks of Working Memory in Dementia: a Proof-of-concept Study
This trial is testing whether precisely timed magnetic pulses to the brain — triggered by a person's own brainwave activity captured on EEG — can improve working memory in people already diagnosed with Alzheimer's disease or a related dementia. The device used is called TMS, transcranial magnetic stimulation. This is a Phase NA proof-of-concept study, meaning researchers are at the very early stage of asking whether the idea is even worth pursuing further.
You may qualify if
- Individuals must be diagnosed with Alzheimer's Disease or related dementias by a clinician.
- Individuals must exhibit adequate oral communication skills and cognitive function sufficient to obtain a score above 10 on the MMSE
- Instructions will be delivered in English; therefore participants must demonstrate an understanding of instruction provided in English.
- Individuals must be at least 55 years or older
You're excluded if
- Contraindications to TMS; presence of a pacemaker, metal/electrical/magnetic implants not including titanium, known history of untreated or uncontrolled psychological disorders, pregnancy, history of seizure or diagnoses of epilepsy, are taking any prescription medications that increase the risk of seizure.
- Allergy to rubbing alcohol, which is needed to prepare electromyography for TMS
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-07-07