NCT07690865 · NOT YET RECRUITING

Investigating the Effectiveness of Personalized Optimal Gamma Auditory Frequency Stimulation Intervention on Cognitive Function Enhancement

This study tests whether listening to gamma-frequency sounds tuned to each person's own brain rhythm improves thinking skills and brain synchronization more than a generic, non-optimal frequency. Twenty healthy adults try both versions for one month each. Researchers measure brain activity with EEG and executive function tasks. It is a small device study with no phase label, so early-stage.

You may qualify if

  • Age between 18 to 40 years old.
  • The Cognitive Abilities Screening Instrument (CASI) score is within normal ranges adjusted for age and education.
  • Participants have no history of severe neurological or psychiatric disorders (such as stroke, epilepsy, depression, migraine, etc.) that could affect cognitive function.
  • Participants have not used drugs that may affect cognitive function (e.g., benzodiazepines, anticholinergic medications, etc.).
  • Participants with normal or corrected vision (e.g., glasses or contact lenses) to normal levels.
  • Auditory stimuli induce significant neural entrainment.
  • Self-reported normal hearing

You're excluded if

  • Participants enrolled in any cognitive enhancement study within the past two months.
  • Participants with a history of disease that could affect cognitive function (e.g., cancer, autoimmune diseases, etc.).
  • Individuals with tinnitus or hyperacusis

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-07-16

View full record on ClinicalTrials.gov

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