NCT07880275 · RECRUITING

Clinical Cohort of Memory Disorders

This is an observational study, meaning no treatment is given. Researchers at three Severance Hospital sites in Korea will collect a small blood sample, along with cognitive tests and brain scans, from about 1,550 people. They will bank the samples to look for blood markers of memory disorders. No phase applies. Nothing is being tested for effectiveness.

Eligibility criteria

Inclusion criteria Memory disorder cohort: Adults of either sex aged 50 years or older.
Healthy young adult controls: Adults of either sex aged 19-30 years. Participants must consent to participation. For patients with limited consent capacity and MMSE \<15, additional consent from a family representative is obtained.
Exclusuion Criteria Memory disorder cohort: Uncontrolled acute or chronic infection, or another life-threatening systemic illness.
Healthy young adult controls:
1. Any current self-reported medical, surgical, neurological, or psychiatric condition.
2. Self-reported history of liver, kidney, or heart disease.
3. Daily medication use.
4. Alcohol consumption on the day before blood collection.
5. Severe impact to the head within the past year, including a motor vehicle accident or fall.
6. Loss of consciousness for any reason within the past year.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-10-19

View full record on ClinicalTrials.gov

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