NCT05881239 · RECRUITING
Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD
This study is testing a smell-based assessment tool called the AROMHA Brain Health Test to see whether changes in the sense of smell can help identify early signs of neurodegenerative disease. Participants sniff physical scratch-and-sniff cards and answer questions through a web app. It is not a drug trial and does not list a phase, meaning it is focused on validating a diagnostic tool rather than testing a treatment.
You may qualify if
- A clinical or research consensus diagnosis of the patient's condition or control status.
- Individuals that are at least 18 years of age at the time of enrollment.
- Individuals that are no older than 100 years of age at the time of enrollment.
You're excluded if
- Primary pulmonary disease such as severe emphysema or asthma not under good medical control.
- Current sinusitis, common cold, upper respiratory infection, or nasal polyps.
- Current or recent (past 6 months) alcohol or substance dependence. A prior history of alcohol or substance abuse will not be grounds for exclusion.
- Pregnancy.
- Severe cognitive dysfunction that would preclude completion of the olfactory testing.
- An adverse reaction to fragrances (ie. they trigger a severe asthmatic attack or nausea).
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-03-06