NCT07755631 · NOT YET RECRUITING
The BASIC-S Feasibility Study for Vascular Risk Reduction
This trial is testing a behavioral coaching program called BASIC-S, which targets six lifestyle areas: blood pressure, physical activity, sleep, social connection, nutrition, and support from a partner. Participants get motivational coaching, video check-ins, text message reminders, and a digital workbook. It is a feasibility pilot — meaning researchers are checking whether the program is practical and acceptable before running a larger trial. It is not yet proven to prevent dementia or stroke.
You may qualify if
- Adults aged 18 years and older currently employed at or recently retired from the London Health Sciences Centre (LHSC) or Western University (with an operational focus on pre-retirees aged 50 years and older).
- Spouse or cohabitating partner of an enrolled primary participant (partner enrollment is optional but strongly encouraged).
- Capable of providing informed consent.
- Access to a mobile device capable of receiving short message service (SMS) communications and viewing PDF documents.
- Physical ability to perform light-to-moderate physical activity.
You're excluded if
- Medical conditions precluding safe exercise (e.g., unstable angina, uncontrolled arrhythmia, severe heart failure) without physician clearance.
- Active or unstable psychiatric conditions, defined as hospitalization for psychiatric care within the preceding 6 months or modifications to antipsychotic or mood-stabilizing pharmacotherapy within the preceding 3 months. (Note: Participants with stable, medically managed psychiatric conditions remain eligible).
- Severe cognitive impairment preventing the ability to consent or use study technology.
- Inability to read and understand English.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-08-10