Optical Coherence Tomography in Neurological Practice: Utility and Applicability Across Neurological Diseases (OCt.IN.N)

Eligibility criteria

Inclusion Criteria for neurological patients:
1. Diagnosis of a Central Nervous System neurological disease (inflammatory diseases such as Multiple Sclerosis; neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease; migraine/headache) according to currently accepted diagnostic criteria for each condition.
2. Age greater than 18 years.
3. Signed informed consent to study participation.
4. Willingness and ability to undergo all study visits and procedures.
Inclusion Criteria for healthy controls:
1. Absence of neurological disease.
2. Age greater than 18 years.
3. Signed informed consent to study participation.
4. Willingness and ability to undergo all study visits and procedures.
Exclusion Criteria for neurological patients:
1. Refusal to participate or withdrawal of informed consent.
2. Known or confirmed ocular pathology identified during examination (ophthalmological evaluation may be requested at the investigators' discretion).
3. Inability to understand instructions given by investigators.
4. Presence of any condition that, in the investigators' opinion, renders the subject unsuitable for the study.
5. For specific imaging modes using clearly visible light sources (MultiColor, FA, BAF): diagnosis of epilepsy or history of previous epileptic seizures.
Exclusion Criteria for healthy controls:
1. Refusal to participate or withdrawal of informed consent.
2. Known or confirmed ocular pathology identified during examination.
3. Inability to understand instructions given by investigators.
4. Presence of any condition that, in the investigators' opinion, renders the subject unsuitable for the study.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-07-22