NCT04389437 · RECRUITING
OCT-Angiography and Adaptive Optics in Patients With Memory Impairment
This pilot study uses two painless eye-imaging techniques, OCT-angiography and adaptive optics, to look at the tiny blood vessels and structure of the retina. Researchers will compare people with memory disorders to people without them, to see if eye patterns differ by cause. It is an early, small study with no drug involved, not a test of any treatment.
You may qualify if
- Patient presenting in memory consultation for memory complaint or person accompanying a patient in memory consultation for memory complaint
You're excluded if
- pregnant or lactating women
- history of known non-degenerative neurological pathology (tumor, stroke territorial, in particular multiple sclerosis)
- history of retinal pathology
- ametropia greater in absolute value than 3 diopters on the sphere, or/and 1.5 diopters on the cylinder.
- history of taking ethambutol for more than 2 months
- history of takingsynthetic antimalarial for more than 2 years
- Mini Mental State Score (MMS) and / or Montreal Cognitive Assessment (MoCA) \<10 for patients and 26 for accompanying persons
- MRI contraindication (for patients only)
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-09-29