Lewy body dementia trials.

This is an observational study, not a drug test. Researchers in Southampton, UK are using yearly blood tests and clinical check-ups over two years to see…

This study gives people with early Lewy body disease either donepezil (Aricept) or a placebo, in a crossover design. Researchers want to know whether EEG…

This is an observational study, not a drug test. Researchers follow people with synucleinopathies, such as Parkinson disease, Lewy body dementia, and multiple…

This is an observational study, not a drug test. People with Parkinson's disease or related conditions fill out online questionnaires every six months for five…

This study takes a person's own bone marrow stem cells and delivers them through a vein and the lower nose. Researchers want to see whether neurologic function…

This study looks at how Alzheimer's disease, Lewy body dementia, and Parkinson's disease differ from one another. Researchers use brain scans (DaTscan, amyloid…

BioFINDER 2 is an observational study in Sweden. It uses brain scans (amyloid and tau PET), spinal fluid tests, and MRI to track how Alzheimer's and related…

This study uses non-invasive eye-imaging technology — optical coherence tomography (OCT) and wide-field retinal photography — to look for early signs of…

This is an observational study, meaning no drug or treatment is being tested. Researchers across Canada will follow people aged 50 to 90 over time, including…

This study records biological signals from the nervous system while participants perform everyday movements like walking and pointing, and practice slow…

This trial is testing whether a single IV infusion of zoledronic acid, a bone-strengthening drug already approved for osteoporosis, can reduce fractures in…

This Phase 4 trial is testing whether measuring the actual blood levels of two common dementia drugs, donepezil and memantine, helps doctors fine-tune the dose…

This trial is testing NYX-458, an experimental oral drug, against a placebo in people who have mild cognitive impairment or mild dementia caused by Parkinson's…

This trial uses a special PET scan tracer called F-DOPA to measure dopamine production in the brain. It is studying people with autonomic nervous system…

This trial compares two ways of testing for sleep apnea in people with memory problems or dementia: a sleep test done at home versus an overnight stay in a…

This pilot study uses two painless eye-imaging techniques, OCT-angiography and adaptive optics, to look at the tiny blood vessels and structure of the retina.…

This trial tests whether ambroxol, an existing drug, is safe and well tolerated over 52 weeks in people with Lewy body dementia. It also looks at whether it…

This trial is testing whether ambroxol, a drug that boosts an enzyme called GCase, can slow cognitive decline, functional loss, and behavioral symptoms in…

This trial is testing how to get the clearest possible pictures from a PET scan that uses a tracer called 18F-DOPA, along with a diuretic, furosemide. It also…

This is an observational study at the University of Pennsylvania — no drug or treatment involved. Researchers are building a long-term data repository by…

This small pilot trial is testing whether terazosin, an existing blood pressure and prostate drug, is tolerable for people with dementia with Lewy bodies.…

This study collects cerebrospinal fluid, the fluid around the brain and spine, through a lumbar puncture (spinal tap). Researchers want to see whether…

This is not a treatment trial. It is a research database at the University of Pennsylvania that collects long-term clinical information, biological samples,…

This trial tests whether telehealth video visits can improve access to specialized, team-based care for people with Lewy body dementia. Instead of traveling to…

This is an observational cohort study based at a major Chinese hospital. Researchers are following elderly Chinese patients who already have a confirmed…

This trial tests whether repetitive transcranial magnetic stimulation, a non-invasive device that uses magnetic pulses on the scalp, can ease cognitive…

This trial tests whether training community doctors in palliative care, combined with telemedicine support, improves quality of life for people with…

This trial tests whether a gentle, non-invasive brain stimulation device, applied to the scalp over the back of the brain at 40 Hz, can improve symptoms in…

This study is testing whether near-infrared spectroscopy, a light-based brain scan, can detect changes in brain oxygen use and metabolism in people with…

This study is testing a diagnostic tool called the Syn-One Test, which looks for a protein called alpha-synuclein in a skin biopsy. The goal is to better…

This trial tests whether a non-invasive device that sends gentle focused ultrasound waves through the skull can help people with early-stage Lewy body…

This trial is validating a new neuropsychological test called REALSoCog, a serious video game designed to detect social behavior problems in people with…

This trial compares two existing antipsychotic drugs, pimavanserin and quetiapine, in people with Lewy body disease who have hallucinations or delusions. It…

This trial tests a one-page tool called the Jumpstart Guide, given to doctors before a clinic visit, to see if it helps them have better conversations with…

This study tests whether a lab method called RT-QuIC can help doctors diagnose dementia with Lewy bodies more accurately. It checks the test in different body…

This study uses digital tools, like devices that track daily symptoms, to build computer models that capture the ups and downs of dementia with Lewy bodies. It…

This trial is testing whether a technology-based matching program can connect dementia caregivers with peer support partners more effectively than random…

This study is building a research foundation — enrolling people with REM sleep behavior disorder (RBD) and healthy controls to prepare for future trials of…

This trial is testing whether a mild electrical brain stimulation technique called tDCS can help people with Lewy body diseases, specifically Parkinson's…

This is a genetic research study, not a treatment trial. Researchers at a memory clinic will collect blood samples from people with suspected or confirmed…

This survey study is collecting information about environmental exposures, work history, and reproductive health to understand what factors might contribute to…

This study uses brain scans (MRI), brain wave recordings (EEG), and muscle activity tests (EMG) to track how memory, thinking, and movement change over time.…

This study looks at whether combining brain wave recordings (EEG), MRI scans, blood and spinal fluid markers, and memory test scores can help doctors spot…

This study tests a new imaging tracer, [11C]SY08, that may let a PET scan show clumps of a brain protein called alpha-synuclein. These clumps are linked to…

This trial tests a new heart-imaging PET scan, called MFBG, to see whether it can help tell apart Parkinson's disease from multiple system atrophy, and Lewy…

This Swedish study is testing whether blood-based biomarkers and cognitive assessments can accurately detect Alzheimer's disease and other forms of cognitive…

This Swedish study is testing whether new blood tests can replace spinal fluid tests for diagnosing memory and dementia conditions. Researchers are comparing…

This is a biobank study, not a treatment trial. NYSCF is collecting blood, skin, or saliva samples from people with various diseases — including Alzheimer's —…

This is not a clinical treatment trial. It is a Finnish records-based research study examining whether people later diagnosed with a neurodegenerative disease…

This Italian observational study is testing whether cognitive screening done by telephone works as well as standard in-person testing for people with…