NCT04706910 · Phase 3 · RECRUITING
18F-DOPA II - PET Imaging Optimization
This trial is testing how to get the clearest possible pictures from a PET scan that uses a tracer called 18F-DOPA, along with a diuretic, furosemide. It also looks at how the tracer shows up in the gallbladder. It is an imaging study, not a therapy. Phase 3 here means a late-stage check of a scan method.
You may qualify if
- Pediatric patients (less than 18 years old) with congenital hyperinsulinism.
- Pediatric patients (less than 18 years old) with neuroblastoma.
- Pediatric (less than 18 years old) or Adult patients (18 or older) with known or clinically suspected neuroendocrine tumor.
- Adult patients (18 or older) with a clinical suspicion of Parkinson's disease or Lewy body dementia.
- Pediatric (less than 18 years old) or Adult patients (18 or older) with brain tumors.
You're excluded if
- Unable to obtain consent
- Weight >225 kg (weight limitation of PET/CT scanner)
- Adult patients unable to lie flat for 20-30 minutes to complete the PET-CT session.
- Young pediatric patients (less than 13 years old) who are unable to lie flat for 20-30 minutes and for whom clinical sedation is contraindicated (as determined by a pediatric anaesthesiologist).
- Lack of intravenous access
- History of previous cholecystectomy (excluded from dynamic abdomen sub-study only)
- Pregnancy
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-02-09