NCT06493422 · RECRUITING

Online Interplay Between Deciding and Acting With Mild Cognitive Impairment

This study is watching how people with mild cognitive impairment make decisions and move their arms at the same time — specifically how quickly the brain coordinates deciding and acting. Researchers are tracking reaching movements to find early biological markers of cognitive decline. This is a Phase NA study, meaning it is observational research, not a drug or treatment trial. No intervention is being tested for effectiveness.

Inclusion criteria

  • age 45 - 90 years
  • Perfect or corrected vision
  • Ability to reach
  • Neurotypical Age-Matched control participants - No history of neurological disorders or injury.
  • Mild Cognitive Impairment participants - clinical diagnosis of amnestic mild cognitive impairment.

Exclusion criteria

  • Any injury or condition that impacts reaching
  • Traumatic brain injury, such as concussion, in the last 6 months.
  • Neurotypical Age-Matched control participants: Modified Telephone Interview for Cognitive Status (TICS-m) score \< 34
  • Mild Cognitive Impairment participants: Modified Telephone Interview for Cognitive Status (TICS-m) score > 34
  • Mild Cognitive Impairment participants: Mini-Mental State Examination Second Edition (MMSE-2) score \< 21.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2025-10-15

View full record on ClinicalTrials.gov

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