NCT06493422 · COMPLETED

Online Interplay Between Deciding and Acting With Mild Cognitive Impairment

Sponsor: University of Delaware

This study is watching how people with mild cognitive impairment make decisions and move their arms at the same time — specifically how quickly the brain coordinates deciding and acting. Researchers are tracking reaching movements to find early biological markers of cognitive decline. This is a Phase NA study, meaning it is observational research, not a drug or treatment trial. No intervention is being tested for effectiveness.

You may qualify if

  • age 45 - 90 years
  • Perfect or corrected vision
  • Ability to reach
  • Neurotypical Age-Matched control participants - No history of neurological disorders or injury.
  • Mild Cognitive Impairment participants - clinical diagnosis of amnestic mild cognitive impairment.

You're excluded if

  • Any injury or condition that impacts reaching
  • Traumatic brain injury, such as concussion, in the last 6 months.
  • Neurotypical Age-Matched control participants: Modified Telephone Interview for Cognitive Status (TICS-m) score < 34
  • Mild Cognitive Impairment participants: Modified Telephone Interview for Cognitive Status (TICS-m) score > 34
  • Mild Cognitive Impairment participants: Mini-Mental State Examination Second Edition (MMSE-2) score < 21.

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-07-06

View full record on ClinicalTrials.gov

All APOE4 clinical trials