NCT07796347 · NOT YET RECRUITING
Dyadic Life Review Intervention for Older Patients With Advanced Cancer and Alzheimer's Disease and Related Dementias and Their Caregivers
This study tests a talk-based therapy called Dyadic Life Review, done together by older adults with advanced cancer and cognitive impairment and their family caregivers. It measures whether the therapy eases caregiver stress and burden. It's an early-stage behavioral study, not a drug trial, so it's about whether this approach helps, not a proven treatment.
Eligibility criteria
Inclusion Criteria: * Age ≥65 * Stage III or IV cancer diagnosis, of any type * The Montreal Cognitive Assessment (MoCA) in-person or MoCA-telephone version ≥15 * Katz Activities of Daily Living (ADL) ≥5 * Able to read and understand English * Be able to provide informed consent (as measured by UBACC) or have a Legally Authorized Representative to provide informed consent, which can include the participating caregiver. Caregiver Inclusion Criteria: * Age 50 or older * Caregivers are defined is a "significant other, spouse, romantic partner, or adult child with whom you discuss or who can be helpful in health-related matters;" * Modified Caregiver Strain Index ≥ 5 * Able to read and understand English Patient Exclusion Criteria: * No caregiver willing to participate in the study Caregiver Exclusion Criteria: • Caregivers unable to provide consent
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-09-01