NCT06940687 · ACTIVE NOT RECRUITING

Neurophysiological Benefits of Live Music for Early Alzheimer's Patients and Their Caregivers

This study looks at how live versus recorded music affects anxiety and brain-heart activity in people with early Alzheimer's, dementia, or MCI and their caregivers. Researchers measure heart rate, heart rate variability, and brain waves (EEG) during music sessions. It's an early-stage study, not testing a treatment, just observing physiological responses to music.

You may qualify if

  • Clinical Dementia Rating 0.5 - 2
  • Be a person with or caregiver to a person with a diagnosis of early Alzheimer's Disease, mild dementia, and/or mild cognitive impairment (MCI)
  • Able to provide informed consent
  • Willing to wear an EEG headset and heart rate monitoring devices
  • Willing to possibly have small patches of body / facial hair shaved to accommodate administration of heart rate monitoring devices
  • Willing to answer survey questions about topics related to the study
  • Willing to be audio / video recorded

You're excluded if

  • Clinical Dementia Rating \<0.5 or > 2
  • Unable to provide informed consent
  • Endorsing suicidal ideation (SI), self-injurious behavior, or homicidal ideation (HI) above the threshold defined in the "Risk Reduction and Safety Plan"
  • Participating in another clinical trial studying AD and/or Dementia
  • Starting a new prescription medication in the last 6 months
  • Prescribed Benzodiazepines on an as needed basis

The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.

Eligibility criteria as of 2026-09-04

View full record on ClinicalTrials.gov

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