NCT02485730 · ACTIVE NOT RECRUITING
Early Identification of Markers in Alzheimer's Families / ALFA
The ALFA study is a long-term observational study — no drug or treatment is being tested. It follows adult children of Alzheimer's patients, tracking biological and physical markers over time to understand what happens in the brain years before any symptoms appear. Observational means researchers are watching and measuring, not intervening. Details on current enrollment status are limited.
You may qualify if
- Adult children of AD patient: First-degree descendant of an AD patient (following diagnosis as define in protocol).
- Age: 45 to 64 years old.
- Long-term commitment to the study: baseline and follow-up visits. Potential participants have to agree to undergo to all the procedures described in the protocol.
You're excluded if
- Cognitive impairment: to be included the participant must show no signs of objective cognitive impairment.
- Any significant systemic illness or unstable medical condition which could lead to difficulty complying with the protocol.
- Illiteracy or functional illiteracy.
- Any contraindication to any test or procedure at the time of study inclusion.
- Family history of monogenic AD.
- Not willing to undergo one or more of the tests and procedures described in the protocol at baseline.
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-05-31