NCT07110207 · RECRUITING
Single-centre Descriptive Study of Taste in Frontotemporal Lobar Degeneration Through the Analysis of Taste Evoked Potentials
This study looks at how the brain responds to a sweet taste in people with frontotemporal lobar degeneration, a different dementia from Alzheimer's. Researchers use a painless scalp recording of brain activity while participants taste a sugar solution. It is a one-morning observational-style study, not a test of any drug, so there is no phase.
You may qualify if
- Person who has given their free and informed consent
- Person of legal age
- Fasting > 2 hours before PEG measurement
- Body Mass Index (BMI) \< 30 kg/m² (according to medical record data)
- DLFT: diagnostic criteria for established or probable DLFT
You're excluded if
- Persons not affiliated with or not covered by a social security scheme
- Persons subject to legal protection measures (guardianship, trusteeship)
- Persons subject to judicial protection measures
- Pregnant women, women in labour or breastfeeding women
- MMSE score \< 15 and/or MoCA score \< 10
- Known COVID-19 infection within 6 months prior to inclusion
- Active smokers (> 4 cigarettes per day on a regular basis)
- Subject with a pacemaker (contraindication for bioelectrical impedance analysis)
- Subject with diabetes (type 1 or type 2)
- Taking medication (during the study) that interferes with taste
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2025-08-24