NCT07638046 · Phase 2 · RECRUITING
Mindful Walking Neural Correlates of Executive Function in SC Older Adults at Risk of Dementias
This trial is testing whether mindful walking, which pairs gentle strolling with mindfulness practice, does more to support brain function and thinking skills in older adults at dementia risk than walking alone. Researchers will use a lightweight, non-invasive brain imaging tool called fNIRS to measure changes in brain activity. It is a Phase 2 pilot trial, meaning it is designed to gather early evidence on whether the approach works, not to prove it definitively.
Eligibility criteria
Inclusion Criteria: 1. Age 60 or older 2. Sedentary (sit ≥9hrs per day) and not meeting the US physical activity guidelines 3. Have at least one of the following ADRD risk factors: i. family history of ADRD (>= first-degree relative) ii. subjective experience of cognitive complaints iii. currently overweight or obese (BMI≥25) 4. Adequate hearing, visual and cognitive ability to complete study tasks and assessments 5. Able to walk without others' assistance 6. Medically stable with or without medication (do not expect to have major health status changes or a surgery in the next 4 months) Exclusion Criteria: 1. Diagnosis of ADRD or other brain abnormalities (i.e., strokes, epilepsy, Parkinson's disease) 2. Diagnosis of mental disorders (i.e., depression) 3. Inability to complete surveys on mobile device or wear the activity monitor (i.e., due to arthritis, physical limitations, or other reasons) 4. Plan to move or have surgery in next 4 months 5. Currently participate in other study involving physical activity or cognitive training that may interfere with the study outcomes 6. Unable to provide consent due to disabilities
The sponsor's own eligibility wording, lightly reformatted. The study team makes the final eligibility decision — worth discussing with your doctor.
Eligibility criteria as of 2026-06-16